Advanced Chemical Biology (eBook, ePUB)

Chemical Dissection and Reprogramming of Biological Systems
Redaktion: Hang, Howard C.; Prescher, Jennifer A.; Pratt, Matthew R.

• Format: ePub

Produktbeschreibung

The book is organized around the central dogma of life, progressing from genes to proteins and higher-order cellular structures. Core application areas such as imaging, chemical genetics, activity-based protein profiling, and natural product discovery and biosynthesis are coverd in the core section of the book. Additional advanced topics and applications in, e. g., microbiology, developmental biology, and neurobiology are covered in the supplemental section. Every chapter is homogeneous in style and layout, consisting of a short historical introduction followed by a description of the underlying concepts and a selection of recent examples how the concept has been turned into practice. With its broad scope and focus on turning ideas into applications, this textbook will serve as a starting point for anyone entering the field and looking for a guide to the wide range of available methods and strategies that chemical biology has to offer.

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Produktdetails

• Verlag: Wiley-VCH
• Erscheinungstermin: 6. Februar 2023
• Englisch
• ISBN-13: 9783527826308
• Artikelnr.: 69438451

Autorenporträt

Howard C. Hang, PhD, Scripps Research, La Jolla, USA. Matthew R. Pratt, PhD, University of Southern California, Los Angeles, USA. Jennifer A. Prescher, PhD, University of California, Irvine, USA.

Inhaltsangabe

Introduction to Advanced Chemical Biology
DNA Function, Synthesis and Engineering
Chemical Approaches to Genome Integrity
RNA function, synthesis, and probing
Chemical Approaches to Transcription and RNA Regulation In Vivo
Chemical Biology of Genome Engineering
Peptide Synthesis and Engineering
Protein Synthesis and Engineering
Directed Evolution for Chemical Biology
Chemical Biology of Cellular Metabolism
Chemical Biology of Lipids
Protein Post-Translational Modifications
Chemical Glycobiology
The Chemical and Enzymatic Modification of Proteins
Genetic Code Expansion
Bioorthogonal Chemistry
Cellular Imaging
In Vivo Imaging
Chemical Biology of Metals
Chemical Approaches Towards Redox Biology
Activity-Based Protein Profiling
Chemical Genetics
Natural Product Discovery
Natural Product Biosynthesis
Chemical Microbiology
Chemical Approaches to Analyze Biological Mechanisms and Overcome Resistance to Therapeutics
Chemical Developmental Biology
Chemical Immunology
Chemical Neurobiology
Small Molecule Drug Discovery

Rezensionen

Interessante Richtung des Lehrbuches, stärker aus chemischer Perspektive betrachtet. Erweitert dadurch den Blickwinkel aufs Fach gerade für Wissenschaftler die stärker aus der biologischen Richtung kommen.
Prof. Dr. David Kostner, Hochschule München, Biotechnologie (11/2023)