Thomas W. Traut

Allosteric Regulatory Enzymes (eBook, PDF)

• Format: PDF

Produktbeschreibung

All enzymes have the ability to increase the rate of a chemical reaction, often by more than a billion-fold. Allosteric enzymes are particularly remarkable because they have the additional ability to change the reaction rate in response to cellular activators or inhibitors. This enables them to control the pathway in which they are the regulatory enzyme. This book covers the most recent developments in the analysis of allosteric enzymes, focusing on those features that are invaluable to the discussion of allosterism and regulation. It introduces the limits for enzyme function as dictated by the factors that constitute the limits for life, and it describes all the mechanisms used for changing enzyme activity. Eight enzymes are used as model systems after extensive study of their mechanisms. The market for this book includes biochemists, molecular biologists, cell biologists, chemists, and biophysicists.

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Produktdetails

• Verlag: Springer US
• Seitenzahl: 250
• Erscheinungstermin: 11. September 2007
• Englisch
• ISBN-13: 9780387728919
• Artikelnr.: 37286300

Autorenporträt

Thomas Traut has a PhD in molecular biology and has studied enzymes since 1974. As a professor at the University of North Carolina at Chapel Hill, he has focused on enzyme regulation and taught advanced enzymology to graduate students. Important findings from his research helped to define the mechanism of allosteric control for dissociating enzymes.

Inhaltsangabe

Overview Of Enzymes.- To Enzymes.- The Limits For Life Define The Limits For Enzymes.- Enzyme Kinetics.- Properties And Evolution Of Allosteric Enzymes.- Kinetics Of Allosteric Enzymes.- K-Type Enzymes.- Hemoglobin.- Glycogen Phosphorylase.- Phosphofructokinase.- Ribonucleotide Reductase.- Hexokinase.- V-Type Enzymes.- To V-Type Enzymes.- G Proteins.- Protein Kinases.

Rezensionen

From the reviews: "This holistic introduction to enzymes in general covers the history of their discovery and the different mechanisms of action before going into an in-depth presentation of particular allosteric enzymes and enzyme families. ... This book will be of great help to graduate students and postdoctoral fellows interested in understanding the theory behind the action of allosteric enzymes. ... an excellent book of enzymology focusing on the mechanisms employed by allosteric enzymes and their metabolic regulation." (Helen Anni, Doody's Review Service, October, 2008)