An Introduction to Biomaterials (eBook, ePUB)

Redaktion: Hollinger, Jeffrey O.

• Format: ePub

Produktbeschreibung

The second edition of this popular text includes nine new chapters that provide a comprehensive and up-to-date educational framework for biomaterials education. A new chapter on the biology of wound healing sets the stage for the basic requirements of standardized biomaterials testing and explains the reactions between biomaterials and the living system into which it is implanted. The book explains in vitro and in vivo testing paradigms and provides numerous examples in the chapters on experimental design, laboratory assays, and animal models. Emphasizing the importance of the regulatory process, it describes how innovation in the biomaterials process relates to patentability and inventorship.

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Produktdetails

• Verlag: Taylor & Francis eBooks
• Erscheinungstermin: 28. November 2011
• Englisch
• ISBN-13: 9781040069349
• Artikelnr.: 72519975

Autorenporträt

Dr. Jeffrey O. Hollinger graduated from Hofstra University in 1969 and received a dental degree and PhD from the University of Maryland in 1973 and 1981, respectively. In addition, he completed a dental residency program and craniofacial fellowship in the U.S. Army Dental Corps. Since 2000, Dr. Hollinger has been a tenured professor at Carnegie Mellon University (CMU) in the departments of biomedical engineering and biological sciences. He is the director of the Bone Tissue Engineering Center at CMU. From 1993 to 2000, he was a tenured professor at the Oregon Health Sciences University in the departments of surgery and developmental biology, and he directed the Northwest Wound Healing Center. In 1993 Dr. Hollinger retired from the U.S. Army as a colonel after serving 20 years of active duty. During that period, he was the director of the Army's Bone Program, as well as the director of the Department of Physiology and Biochemistry at the U.S. Army Institute of Dental Research at the Walter Reed Army Medical Center in Washington, DC. He has over 35 years of experience in bone regeneration using biological factors, biomaterials, and preclinical animal models. Dr. Hollinger has received numerous federal grants as the principal investigator (NIH, NSF, DoD, and NIST) focusing on applied and fundamental sciences for bone regeneration and is engaged with several industrial groups emphasizing bone regenerative therapeutics, as well as serving on corporate boards. Dr. Hollinger has several patents and has licensed technology developed in his lab. He received the prestigious Clemson Award in biomaterials in 2008. He has over 250 peer-reviewed publications, abstracts, book chapters, and books.

Inhaltsangabe

Consensus Definitions, Fundamental Concepts, and a Standardized Approach to
Applied Biomaterials Sciences. Biology, Biomechanics, Biomaterial
Interactions: Wound Healing Biology. Cutaneous Wound Pathobiology: Raison
d'etre for Tissue Engineering. Osseous Wound Healing. Biology,
Biomechanics, Biomaterial Interactions: Cellular Mechanics. Cell and Tissue
Mechanobiology. Biology, Biomechanics, Biomaterial Interactions:
Materials-Host Interactions. Cell-Material Interactions: Fundamental Design
Issues for Tissue Engineering and Clinical Considerations. Host Response to
Biomaterials. Protein Adsorption at the Biomaterial-Tissue Interface.
Biomaterials Testing, Statistics, Regulatory Considerations, Intellectual
Property: Standardized Materials Testing. In Vitro Testing of Biomaterials.
Assessment of Biomaterials: Standardized In Vivo Testing. Biomaterials
Testing, Statistics, Regulatory Considerations, Intellectual Property:
Statistics. Basic Principles of Statistics: Considerations for Biomaterials
Engineers. Therapy Development, Animal Testing, and Regulatory Issues.
Fundamentals of Patenting for the Biomaterials Scientist. Biomaterials
Compositions. Proteins and Amino Acid-Derived Polymers. Three-Dimensional
Fibrin Constructs in Tissue Engineering. Biomedical Polyurethanes. Polymers
Derived from l-Tyrosine. Poly(propylene Fumarate). Complex Polysaccharides:
Chitosan and Alginate. Collagen: A Natural Biomaterial for Tissue
Engineering. Polyphosphazenes. Biologically Active Glasses. Silk-Based
Biomaterials: Biology, Properties, and Clinical Applications. Calcium-Based
Bioceramics: Biology, Properties, and Clinical Applications. Biomaterials
Applications. Tissue Engineering of Skin. Polymeric Biomaterials for Drug
and Nucleic Acid Delivery. Orthopedic Prostheses and Joint Implants. Bone
and Biomaterials. Functional Regeneration of Synovial Joints In Vivo: The
Role of Biomaterials and Scaffold Design. Tissue Engineering, Biomaterials,
and the Nervous System. Ligaments, Biomaterials, and Tissue-Engineering
Opportunities. Cardiovascular Tissue Engineering and Biomaterials. Index.