Big on Bk (eBook, ePUB)

Current Insights into the Function of Large Conductance Voltage- and Ca2+- Activated K+ Channels at the Molecular, Cellular and Systemic Levels

• Format: ePub

Produktbeschreibung

Big on Bk: Current Insights into the Function of Large Conductance Voltage- and Ca2+- Activated K+ Channels at the Molecular, Cellular and Systemic Levels, a volume in the International Review of Neurobiology series, is a comprehensive overview of the state-of-the-art research into this area. It reviews current knowledge and understanding, and also provides a starting point for researchers and practitioners entering the field. - The latest volume in the International Review of Neurobiology series - Provides a broad coverage of subject matter at the molecular, cellular and systemic levels - Presents an ideal resource for researchers and practitioners, and those just entering the field

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 550
• Erscheinungstermin: 26. Mai 2016
• Englisch
• ISBN-13: 9780128036471
• Artikelnr.: 45135045

Autorenporträt

Candice Contet, Ph.D., is Assistant Professor at The Scripps Research Institute (TSRI), La Jolla, CA. She is an NIH-funded investigator with 15 years of experience in the study of drug addiction. She is a member of the Integrative Neuroscience Initiative on Alcoholism (INIA-WEST) consortium funded by NIAAA, and directs the Viral Vector Core of TSRI Alcohol Research Center. She has a documented track record of investigating the molecular changes elicited by drugs of abuse and their relevance to behavioral adaptations. She has authored more than 20 peer-reviewed publications. She is on the editorial board of the journal Frontiers in Molecular Neuroscience. She attended the Ecole Normale Superieure (Paris, France) and obtained her PhD from the University of Strasbourg (France). She completed her research training under the mentoring of Drs. Nick Rawlins, Brigitte Kieffer, Athina Markou and George Koob.

Inhaltsangabe

1. Biophysics of BK channel gating



Riccardo Olcese



2. Modulation of BK channel function by auxiliary beta and gamma subunits



Jiusheng Yan



3. Posttranscriptional and posttranslational regulation of BK channels



Mike Shipston



4. Protein network interacting with BK channels



Hongkyun Kim



5. Functional role of mitochondrial and nuclear BK channels



Tian-Ming Gao



6. Modulation of BK channels by small endogenous molecules and pharmaceutical channel openers



Toshinori Hoshi



7. Modulation of BK channels by ethanol



Alex Dopico



8. BK channels in neurons



Alison Barth



9. BK channels in the pituitary and hypothalamus



Peter Duncan



10. BK channels in the inner ear



Sonja Pyott



11. BK channels in the vascular system



Gayathri Krishnamoorthy-Natarajan



12. Developing the molecular pharmacology of BK channels for therapeutic benefit



Gregory John Kaczorowski