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  • Format: ePub

As the world is experiencing, infectious diseases pose a major threat to public health and global economies, where a lack of rapid and reliable analysis methods hinders effective treatment strategies. Currently, the highest sensitivity for virus detection is achieved using the polymerase chain reaction along with its intrinsic drawbacks; for instance, it has a long processing time and requires advanced laboratory equipment with trained personnel. Biosensors hold great potential to turn our current analytical methods into diagnostic strategies by tailoring their sensing modules for the…mehr

Produktbeschreibung
As the world is experiencing, infectious diseases pose a major threat to public health and global economies, where a lack of rapid and reliable analysis methods hinders effective treatment strategies. Currently, the highest sensitivity for virus detection is achieved using the polymerase chain reaction along with its intrinsic drawbacks; for instance, it has a long processing time and requires advanced laboratory equipment with trained personnel. Biosensors hold great potential to turn our current analytical methods into diagnostic strategies by tailoring their sensing modules for the detection of biomolecules, especially nano-sized objects, such as protein biomarkers and viruses. With recent outbreaks of SARS, MERS and the present COVID-19 pandemic, biosensors detecting viral pathogens offer low-cost, simple-to-use, and rapid solutions. The rapid and cost-effective identification of the presence of a virus in contaminated food or water, surfaces, or in patients is a prerequisite to efficiently counteract viral outbreaks, epidemics as well as bioterrorism.

Being at the intersection of these multiple disciplines, this book is suitable for academic, clinical, and commercial researchers, as well as graduate students. This book reviews the latest studies and developments in the use of a range of biosensor platforms for the analysis of viral infections. Following an introduction to viruses and the importance of virus detection for medical applications, it introduces the properties, fabrication, characterization, applications, and recent research regarding optical, electrochemical, piezoelectric, fluorescence, thermal, magnetic, and micromechanical sensor families. It further embraces state-of-art technological developments that incorporate additional platforms such as microfluidic systems, lab-on-a-chip tools, and molecular imprinting techniques, and also includes relevant chemistry, physics, biology, medicine, and nanotechnology. In each case, the use and potential of each biosensor for viral detection are explained, and these points have been elaborated for the applications in Coronavirus, HIV, Hepatitis, Ebola, Zika, Norovirus, Influenza, SARS, and others.


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