Sylvia Wassertheil-Smoller

Biostatistics and Epidemiology (eBook, PDF)

A Primer for Health and Biomedical Professionals

• Format: PDF

Produktbeschreibung

The recent controversy regarding the efficacy of mamagrams in diagnosing early stage breast cancer revealed to the public previously overlooked aspects of the difficulties of statistical accuracy needed in biomedical research. For those in the field, the public outcry served to remind them that two critical issues cannot be overlooked: study design and the correct analysis and application of the data derived. Surprisingly few academic physicians and scientific researchers truly have a solid understanding of the fundamental principles of statistics and epidemiology. This deficiency is being addressed in medical schools as more and more programs are now including introductory classes in these subjects in their core curicculum.

For the new edition, Dr. Smoller has included several new chapters (genetic statistics, molecular epidemiology, scientific integrity and research ethics) and a new appendix on the basic concepts of genetics and a glossary of genetic terminology. She has also expanded the coverage of multi-center trials (an important aspect of implementation of the standards of evidence-based medicine), controversies in screening for prostate, colon, breast, and other cancers.

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Produktdetails

• Verlag: Springer US
• Seitenzahl: 244
• Erscheinungstermin: 10. Mai 2006
• Englisch
• ISBN-13: 9780387218298
• Artikelnr.: 43999892

Autorenporträt

Sylvia Wassertheil-Smoller, PhD, is professor of epidemiology in the Department of Epidemiology and Population Health at the Albert Einstein College of Medicine and is the Dorothy and William Manealoff Foundation and Molly Rosen Chair in Social Medicine, Emerita. In addition to her teaching, her research spans both cardiovascular disease and cancer epidemiology. She has been a leader in landmark clinical trials in the prevention of heart disease and stroke and in major national and international collaborative prospective studies that have informed guidelines for medical practice. She has won awards for mentoring students and junior faculty, as well as the Einstein Spirit of Achievement Award. She lives in New York. Jordan Smoller, MD, ScD, is professor of psychiatry at Harvard Medical School and professor in the Department of Epidemiology at the Harvard T.H. Chan School of Public Health in Boston. He is director of the Psychiatric and Neurodevelopmental Genetics Unit in the Massachusetts General Hospital (MGH) Center for Genomic Medicine,  director of the Center for Precision Psychiatry at MGH, and an Associate Member of the Broad Institute of MIT and Harvard. The focus of Dr. Smoller's research is understanding the genetic and environmental determinants of psychiatric disorders across the lifespan and using big data to advance precision mental health including improved methods to reduce risk and enhance resilience.  He is the recipient of numerous research awards, an author of more than 500 scientific articles, book chapters and reviews, and author of the book The Other Side of Normal (HarperCollins/William Morrow, 2012). He lives with his family in Boston.

Inhaltsangabe

1. The Scientific Method.- 2. A Little Bit of Probability.- 3. Mostly About Statistics.- 4. Mostly About Epidemiology.- 5. Mostly About Screening.- 6. Mostly About Clinical Trials.- 7. Mostly About Quality of Life.- 8. Mostly About Genetic Epidemiology.- 9. Risk Prediction and Risk Classification.- 10. Research Ethics and Statistics.- Postscript.- Appendix A.- Appendix B.- Appendix C.- Appendix D.- Appendix E.- Appendix F.- Appendix G. References.- Suggested Readings.- Index.