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> 0.5 cm. It is also known as circumscribed cafe-au-lait hyper-melanosis, von Recklinghausen spot, or abbreviated as "CALM". The name cafe au lait is French for "coffee with milk" and refers to their light-brown color. They are produced by a collection of pigment-forming melanocytes in the epidermis of the skin. These spots are typically permanent, and may grow or increase in number over time. Cafe au lait spots are often benign, not harmful but may be linked with syndromes such as neurofibromatosis type 1 and McCuneAlbright syndrome. Cafe-au-lait spots are normally evident at birth…mehr

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Produktbeschreibung
> 0.5 cm. It is also known as circumscribed cafe-au-lait hyper-melanosis, von Recklinghausen spot, or abbreviated as "CALM". The name cafe au lait is French for "coffee with milk" and refers to their light-brown color. They are produced by a collection of pigment-forming melanocytes in the epidermis of the skin. These spots are typically permanent, and may grow or increase in number over time. Cafe au lait spots are often benign, not harmful but may be linked with syndromes such as neurofibromatosis type 1 and McCuneAlbright syndrome. Cafe-au-lait spots are normally evident at birth (congenital) or occur in early infancy. They occasionally become apparent later in infancy, particularly after exposure to the sun, which darkens the color. They may be isolated or linked with systemic diseases such as neurofibromatosis (NF), McCune Albright syndrome, Legius syndrome, and LEOPARD syndrome. Causes: The brown color of a cafe-au-lait spot is because of a pigment called melanin, produced in the skin by cells called melanocytes. Multiple cafe-au-lait spots are related to several genetic syndromes. Neurofibromatosis type 1 &2 Legius syndrome McCune Albright syndrome, LEOPARD syndrome. Symptoms: Cafe-au-lait spots: 1.They are light brown in color. 2.The pigment is evenly distributed. 3.They are well demarcated with smooth or irregular border 4.Their shape is often round or oval Diagnosis Cafe-au-lait spots are diagnosed visually with measurement of spot size If significant in number and size, a complete medical examination should be done to find out whether a related syndrome may be present. Syndromes may be diagnosed from their medical manifestations or by genetic testing 6 or more cafe au lait spots greater than 5 mm in diameter before puberty is a diagnostic feature of neurofibromatosis type I Skin biopsy may be required for certain syndromes. Treatment No medical care is required to treat cafe-au-lait spots. Cafe au lait spots can be removed with lasers. Results are inconsistent as the spots are often not entirely removed or can recur after treatment. Often, a test spot is treated first to help predict the likelihood of treatment success. Lasers reported to have successfully faded cafe-au-lait spots are: 1.Pulsed-dye laser 2.Er:YAG laser 3.Q-switched Nd:YAG laser 4.Q-switched ruby or alexandrite laser Results are not consistent. A study has found lesions with an irregular margin react better than those with a smooth, well-defined border. Risks for laser surgery are: 1.Transient or permanent hyper-pigmentation, 2.Hypo-pigmentation, and 3.Scarring. 4.Permanent hyper-pigmentation, and 5.Recurrence Complete disappearance of cafe au liat spots was documented using a pulsed dye laser for 4-14 treatments, with no repeat occurrences at 12 months follow-up Chinese patients were treated with the Q-switched alexandrite laser and 51.4% patients had good-to-excellent reactions after an average of 3.2 treatments with a low rate of recurrence (10.4%). The results are normally preferred, and when considerable clearing is obtained, the repeat occurrence rate is low; where clearance is partial, repeat occurrence is as high as 50%. The risk of post-inflammatory hyper-pigmentation is as high as 50% per treatment. When this develops, it is essential to wait until it clears before resuming laser treatment. Treatment of underlying syndromes may be complicated and need multidisciplinary care TABLE OF CONTENT Introduction Chapter 1 Cafe-Au-Lait S...


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Autorenporträt
Dr. Kenneth Kee is a well-known medical doctor from Singapore who has been practicing medicine since 1972.
He graduated from the University of Singapore and furthered his studies with a Master of Science in Health Management in 1991, followed by a Ph.D. in Healthcare Administration in 1993.
Dr. Kee established Kee Clinic in 1974, located in the Holland Drive area of Singapore. The clinic has been a prominent feature of the community, offering general medical services for 5 decades.
Dr Kee also served his country Singapore as a national service police Inspector at night from 1975 to 1985 while working at his clinic during the day.
He had served as a police guard to the Woodland Petroleum Tanks at night during the Indonesian Confrontation period, took part in police rounds at night in the Beach Road area and taught First aid and emergency resuscitation to Police recruits.
He received the Singapore Police Bicentennial 2020 Medallion on 1st March 2024 as recognition for his work in the Singapore Police.
Even as he grew older, Dr. Kee continued to work actively in his clinic, although he eventually reduced his consultation hours.
Beyond his medical career, Dr. Kee is also an author.
He started writing about medical conditions in 2007, using blogs and other online platforms to share his knowledge with a broader audience.
Over time, he published various books, many of which provide simple and accessible guides to different health conditions.
His works include "A Family Doctor's Tale," "My Personal Singapore History," and numerous medical guides, available through platforms like Amazon.
His books often combine his personal experiences as a family doctor with insights into Singapore's healthcare system and history.
Dr. Kee has written extensively on health topics, contributing to both medical literature and general knowledge resources.

Dr. Kenneth Kee has written numerous books, primarily focused on health education and personal experiences as a family doctor. Some of his notable titles include:
"A Family Doctor's Tale"
This book is a blend of Dr. Kee's personal experiences and his reflections on being a family doctor in Singapore. It's a great choice if you're looking for a narrative that combines both medical knowledge and human stories.
"Specialized Medical Conditions"
Books like **"Congestive Heart Failure: Diagnosis and Treatment"** focus on specific conditions, offering in-dept...