Calcitonin Gene-Related Peptide (CGRP) Mechanisms (eBook, PDF)

Focus on Migraine
Redaktion: Brain, Susan D.; Geppetti, Pierangelo

• Format: PDF

Produktbeschreibung

This book provides a thorough review of the key recent research into the role of CGRP in health and disease.

In particular, it enables and enriches understanding of CGRP in migraine pathophysiology.

Provides a full update of the latest therapeutic perspectives and clinical advancements with potential therapeutic agents that block the actions of CGRP.

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Produktdetails

• Verlag: Springer International Publishing
• Seitenzahl: 192
• Erscheinungstermin: 31. August 2019
• Englisch
• ISBN-13: 9783030214548
• Artikelnr.: 57607755

Inhaltsangabe

1. CGRP Discovery and Timeline.- 2. CGRP Receptor Biology: Is There More Than One Receptor?.- 3. The Structure of the CGRP and Related Receptors.- 4. CGRP Receptor Signalling Pathways.- 5. Pathways of CGRP Release from Primary Sensory Neurons.- 6. CGRP in Animal Models of Migraine.- 7. CGRP in Human Models of Migraine.- 8. Role of CGRP in Migraine.- 9. Understanding CGRP and Cardiovascular Risk.- 10. CGRP and Painful Pathologies other than Headache.- 11. Calcitonin Gene-Related Peptide Antagonists and Therapeutic Antibodies.