Diane L. Fairclough

Design and Analysis of Quality of Life Studies in Clinical Trials (eBook, ePUB)

• Format: ePub

Produktbeschreibung

Design Principles and Analysis Techniques for HRQoL Clinical TrialsSAS, R, and SPSS examples realistically show how to implement methods Focusing on longitudinal studies, Design and Analysis of Quality of Life Studies in Clinical Trials, Second Edition addresses design and analysis aspects in enough detail so that readers can apply statistical meth

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Produktdetails

• Verlag: Taylor & Francis eBooks
• Erscheinungstermin: 7. Januar 2010
• Englisch
• ISBN-13: 9781040070079
• Artikelnr.: 73153966

Autorenporträt

Diane L. Fairclough is a professor in the Department of Biostatistics and Informatics in the Colorado School of Public Health and director of the Biostatistics Core of the Colorado Health Outcomes Program at the University of Colorado in Denver. She is also President of the International Society for Quality of Life Research. Dr. Fairclough's prior appointments include St. Jude Children's Research Hospital, Harvard School of Public Health, and AMC Cancer Research Center.

Inhaltsangabe

Introduction and Examples. Study Design and Protocol Development. Models
for Longitudinal Studies I. Models for Longitudinal Studies II. Moderation
and Mediation. Characterization of Missing Data. Analysis of Studies with
Missing Data. Simple Imputation. Multiple Imputation. Pattern Mixture and
Other Mixture Models. Random Effects Dependent Dropout. Selection Models.
Multiple Endpoints. Composite Endpoints and Summary Measures. Quality
Adjusted Life-Years (QALYs) and Q-TWiST. Analysis Plans and Reporting
Results. Appendices. References.