Duchenne Muscular Dystrophy (eBook, PDF)

Advances in Therapeutics
Redaktion: Chamberlain, Jeffrey S.; Rando, Thomas A.

• Format: PDF

Produktbeschreibung

Duchenne Muscular Dystrophy (DMD) is one of the most prevalent genetic disorders of childhood for which there is no cure. This authoritative guide provides a clear overview of the clinical, genetic, and pathophysiological aspects of the disease in the context of emerging therapeutic modalities. The only available source on the subject, this reference emphasizes the importance of accurate diagnosis, carrier detection, and genetic counseling, and supplies state-of-the-art information on pharmacological interventions, regenerative medicine, and gene therapy.

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Produktdetails

• Verlag: Taylor & Francis eBooks
• Seitenzahl: 496
• Erscheinungstermin: 27. Februar 2006
• Englisch
• ISBN-13: 9780849374456
• Artikelnr.: 53318357

Autorenporträt

Jeffrey S. Chamberlain, Thomas A. Rando

Inhaltsangabe

Clinical Overview. The Functional Biology of Dystrophin. Duchenne Muscular
Dsytrophy and Becker Muscular Dystrophy: Diagnostic Principles. Mutation
Detection. Protein Studies. Medical Management. Rehabilitation Management.
A Review of Current Practice and Clinical Outcomes.  Therapeutic Principles
and Challenges. Experimental Pharmacologic Therapies. Utrophin: The
Intersection between Pharmacological and Genetic Therapy. Regenerative
Therapy. Cellular-Mediated Delivery: The Intersection between Regenerative
Medicine and Genetic Therapy. Oligonucleotide-Mediated Rxon Skipping and
Gene Editing. Intravascular Delivery of Naked DNA. Adenoviral-Mediated Gene
Therapy. Retroviridae-based Gene Transfer Vectors. Gene Therapy Using
Adeno-Associated Viral Vectors. Regional and Systemic Gene Delivery using
Viral Vectors.