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Engineering of Biomaterials for Drug Delivery Systems: Beyond Polyethylene Glycol examines the combined issues of PEGylation and viable biomaterials as alternatives. With a strong focus on polymeric biomaterials, the book first reviews the major issues associated with PEGylation and its use in vivo. Chapters then focus on alternative polymer systems for drug delivery systems. Finally, nanoparticles and future perspectives are examined. This book is a valuable resource for scientists and researchers in biomaterials, pharmaceuticals and nanotechnology, and all those who wish to broaden their…mehr
Engineering of Biomaterials for Drug Delivery Systems: Beyond Polyethylene Glycol examines the combined issues of PEGylation and viable biomaterials as alternatives. With a strong focus on polymeric biomaterials, the book first reviews the major issues associated with PEGylation and its use in vivo. Chapters then focus on alternative polymer systems for drug delivery systems. Finally, nanoparticles and future perspectives are examined. This book is a valuable resource for scientists and researchers in biomaterials, pharmaceuticals and nanotechnology, and all those who wish to broaden their knowledge in this field.
Provides a self-contained work for the field of biomaterials for drug delivery
Summarizes the current knowledge on PEGylation and strategies for bypassing it
Presents research on an important, though under-represented issue in biomaterials
Written by a world-class team of research scientists, engineers and clinicians
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Autorenporträt
Dr Anilkumar Parambath is Senior R&D Manager of YTY Group, Indorama Corp., Perak, Malaysia. Prior to this, he was R&D Manager, Science & Technology at Unilever (2021-2024); Senior Manager and Head of Capsules Product R&D, ACG Capsules, Mumbai, India (2018-2021) and Principal Investigator for Performance and Specialty Materials at Syngene International Ltd, Bangalore India (2017-2018), where he worked on developing various elastomers, silicones, acrylics and other polymers for biomedical applications. He completed his PhD in Chemistry (Polymer Science) at the University of Kerala, India, and spent 7 years conducting post-doctoral research at Clemson University, USA, French atomic Energy Commission (CEA), France, and the University of British Columbia, Canada. HIs expertise is in polymer science, materials science, green chemistry, nanotechnology, nanomedicine, and biomaterials science. Dr. Parambath has edited three books on polymer biomaterials in drug delivery applications, including two with Elsevier, and has published many books chapters and journal articles. He has two patents to his name. In 2024, he was recognized by the American Chemical Society (ACS) as a Sustainability Star.
Inhaltsangabe
1. PEGylated 'stealth' liposomes 2. PEGylated proteins 3. PEGylation and anti-PEG antibodies 4. Poly (zwitterions) 5. Poly (glycerols) 6. Poly (oxazolines) 7. Poly (aminoacids) 8. Poly (acylamides) and related systems 9. Poly (vinylpyrrolidones) 10. Sugar based systems (trehalose) 11. Polypeptide alternatives (PASylation and XTen) to PEG 12. DDS based on non-immunogenic biopolymers 13. Non-PEGylated nanoparticles 14. Summary and future perspectives
