Essential Tremor: Current Concepts and Controversies (eBook, ePUB)

Redaktion: Kuo, Sheng-Han; Louis, Elan

• Format: ePub

Produktbeschreibung

Tremors, Volume 163 in the International Review in Neurobiology serial highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the International Review on Neurobiology serial - Updated release includes the latest information on Tremors

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 368
• Erscheinungstermin: 21. Juni 2022
• Englisch
• ISBN-13: 9780323899758
• Artikelnr.: 64211589

Autorenporträt

Dr. Kuo is a Movement Disorders specialist caring for patients with cerebellar ataxia, including spinocerebellar ataxia and multiple system atrophy, and a variety of other movement disorders, such as essential tremor and Parkinson's disease. As a physician-scientist, his research is funded by National Institutes of Health to study the role of the cerebellum in movement disorders, implicating in ataxia and tremor. He leads a multi-disciplinary research team(link is external and opens in a new window) to study the disease mechanism and to develop therapies for movement disorders via translational research and clinical trials.

Dr. Kuo is the Director for the Initiative for Columbia Ataxia and Tremor(link is external and opens in a new window) (ICAT), an interdisciplinary research group to study how the cerebellum plays a role in neurological and neurodegenerative disorders. He also serves as one of the tri-leaders for the Clinical Research Consortium for Spinocerebellar Ataxia

s, constituting 15 medical centers in the U.S. to study patients living with spinocerebellar ataxias. Aiming to promote research collaboration, Dr. Kuo organizes International Tremor Congress(link is external and opens in a new window) every other year, bringing researchers together to advance therapies for tremor. He was elected in 2020 as the Vice Chair for the Movement Disorders Section at American Academy of Neurology(link is external and opens in a new window).

Dr. Kuo has received multiple scientific awards as the recognition of his contributions to neurology, including 2016 Louis V. Gerstner Jr. Scholar Merit Award, 2019 American Academy of Neurology Jon Stolk Award for Movement Disorders, and 2020 American Neurological Association Derek Denny-Brown Award.

Inhaltsangabe

1. What's in a name? nomenclature of essential tremor- syndrome or family of diseases?
Louis & Kuo
Is essential tremor a family of diseases or a syndrome? A family of diseases
Riboldi & Frucht
Is essential tremor a family of diseases or a syndrome? A syndrome
Pandey

2. Essential tremor- Is this an electrical or a degenerative disorder? Or is it both?
Louis & Kuo
Is essential tremor a degenerative disorder or an electric disorder? A degenerative disorder
Faust
Is essential tremor a degenerative disorder or an electric disorder? An electric disorder
Cho

3. How important is the inferior olive in essential tremor? An evolving story
Kuo & Louis
Is inferior olive central to the pathophysiology of essential tremor? Yes
Lang & Handforth
Is inferior olive central to the pathophysiology of essential tremor? No
Manto

4. Essential tremor as a harbinger- what is the cognitive fallout of having essential tremor?
Louis & Kuo
Does essential tremor increase the risk of dementia? Yes
Cosentino & Shih
Does essential tremor increase the risk of dementia? No
Rajput

5. Is essential tremor a disorder primarily due to GABA dysfunction?
Kuo & Louis
Is essential tremor a disorder of primary GABA dysfunction? Yes
Gironell
Is essential tremor a disorder of primary GABA dysfunction? No
Bellows &Jimenez-Shahed

6. The future of pharmacotherapies for essential tremor: enhancing GABA neurotransmission or reducing neuronal hyper-excitability?
Kuo & Louis
What is the next generation of medication for essential tremor? Enhancing GABAergic inhibition
Ondo
What is the next generation of medication for essential tremor? Reduction of hyper-excitability
Shukla