>20% circulating Sezary cells indicates Sezary syndrome Skin biopsies from several locations may be taken if the cause is not known. They are likely to reveal non-specific inflammation on histopathology Direct immunofluorescence is of use if an autoimmune blistering disease or connective tissue disease is indicated Treatment: Exfoliative dermatitis is possibly serious, even life-threatening Most patients need hospitalization for monitoring of circulatory status and body temperature and to replace fluid and electrolyte balance. These general measures apply: 1.Stop all medicines that are not needed 2.Check fluid balance and body temperature 3.Retain skin moisture with: a.Wet wraps, b.Other wet dressings, c.Emollients and d.Mild topical steroids 4.Antibiotics are given for bacterial infection 5.Antihistamines may decrease severe itch 6.Specific treatment for psoriasis and skin atopy TABLE OF CONTENT Introduction Chapter 1 Exfoliative Dermatitis...
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