Kenneth Kee

Fibrodysplasia Ossifican Progressiva (Stone Man Syndrome), A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions (eBook, ePUB)

• Format: ePub

Produktbeschreibung

This book describes Fibrodysplasia Ossifican Progressiva, Diagnosis and Treatment and Related Diseases It is hard to believe that genetic mutations can produce abnormal human illnesses such as the Stone Man Syndrome or Werewolf Syndrome. After reading about genetic diseases, I find that there are really such cases found in medical history. Just like the X-men and Incredible Hulk genetic mutations can produce abnormal disorders such as Stone Man Syndrome and Werewolf Syndrome, even Mermaid Syndrome, Tree Man Syndrome and Harlequin Baby. These are really amazing true genetic disorders. In Stone Man Syndrome, muscle and connective tissue such as tendons and ligaments are slowly replaced by bone (ossified), producing bone outside the skeleton (extra-skeletal or heterotopic bone) that restricts movement. There are no other known disorders in medicine of one normal organ system turning into another. There are essential reasons why muscle is muscle and bone is bone. Occasionally the patient requires flexibility and strength. Other times the patient requires hardness and structure. In this rare disorder called fibrodysplasia ossificans progressiva (FOP), this system is disrupted. The body's soft tissues (muscles, ligaments, and tendons) transform into bone and form a second skeleton outside the normal one. As the bone takes over, it becomes harder or even impossible to move different parts of the body, which affects everyday activities such as eating and talking. In this disorder, there is the mutation of a gene in the bone morphogenetic protein (BMP) pathway, which is essential during the formation of the skeleton in the embryo and the repair of the skeleton after birth The ACVR1 protein is present in many tissues of the body such as skeletal muscle and cartilage. It is used to regulate the growth and development of the bones and muscles, such as the gradual replacement of cartilage by bone (ossification) that happens in normal skeletal maturation from birth to young adulthood. Mutations in the ACVR1 gene disrupt the mechanisms that regulate the receptor's activity. As a result, the receptor is activated when it normally should not be. Too much receptor activity produces overgrowth of bone and cartilage, causing the signs and symptoms of fibrodysplasia ossificans progressiva. FOP often begins in early childhood. It starts around the shoulders and neck, then works its way down through the rest of the body. Malformations of the toes and fingers may be evident at birth (congenital). Abnormal development of extra-skeletal bone normally happens during early childhood. In a few rare patients, the start of abnormal bone growth may not happen until late adolescence or early adulthood. Affected patients may have periods of time where they are free of new events of bone growths. The new bone growth can start at any time for no apparent cause (spontaneously). In the affected regions, bone slowly replaces the connective tissue Besides skeletal muscle, bony growths also happen in different tendons, ligaments, and bands of fibrous tissue that support muscles (fascia). The neck, back, chest, arms, and legs are normally the first areas involved. Abnormal development of bone finally causes stiffness and limited motion of affected joints. If the jaw is affected, involved persons may have trouble eating and speaking. As bone replaces tissue, the patient is unable to find the ability to move body parts making it harder to: 1. Breathe 2. Eat 3. Keep the balance 4. Speak 5. Walk or sit FOP may ultimately cause complete immobilization. There is no cure for FOP and treatment is limited to symptoms. TABLE OF CONTENT Introduction Chapter 1 Fibrodysplasia Ossifican Progressiva (Stone Man Syndrome) Chapter 2 Causes Chapter 3 Symptoms Chapter 4 Diagnosis...

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Produktdetails

• Verlag: Kenneth Kee
• Erscheinungstermin: 10. Dezember 2019
• Englisch
• ISBN-13: 9780463308295
• Artikelnr.: 75905075

Autorenporträt

Dr. Kenneth Kee is a well-known medical doctor from Singapore who has been practicing medicine since 1972.
He graduated from the University of Singapore and furthered his studies with a Master of Science in Health Management in 1991, followed by a Ph.D. in Healthcare Administration in 1993.
Dr. Kee established Kee Clinic in 1974, located in the Holland Drive area of Singapore. The clinic has been a prominent feature of the community, offering general medical services for 5 decades.
Dr Kee also served his country Singapore as a national service police Inspector at night from 1975 to 1985 while working at his clinic during the day.
He had served as a police guard to the Woodland Petroleum Tanks at night during the Indonesian Confrontation period, took part in police rounds at night in the Beach Road area and taught First aid and emergency resuscitation to Police recruits.
He received the Singapore Police Bicentennial 2020 Medallion on 1st March 2024 as recognition for his work in the Singapore Police.
Even as he grew older, Dr. Kee continued to work actively in his clinic, although he eventually reduced his consultation hours.
Beyond his medical career, Dr. Kee is also an author.
He started writing about medical conditions in 2007, using blogs and other online platforms to share his knowledge with a broader audience.
Over time, he published various books, many of which provide simple and accessible guides to different health conditions.
His works include "A Family Doctor's Tale," "My Personal Singapore History," and numerous medical guides, available through platforms like Amazon.
His books often combine his personal experiences as a family doctor with insights into Singapore's healthcare system and history.
Dr. Kee has written extensively on health topics, contributing to both medical literature and general knowledge resources.

Dr. Kenneth Kee has written numerous books, primarily focused on health education and personal experiences as a family doctor. Some of his notable titles include:
"A Family Doctor's Tale"
This book is a blend of Dr. Kee's personal experiences and his reflections on being a family doctor in Singapore. It's a great choice if you're looking for a narrative that combines both medical knowledge and human stories.
"Specialized Medical Conditions"
Books like **"Congestive Heart Failure: Diagnosis and Treatment"** focus on specific conditions, offering in-dept...