G Protein-Coupled Receptors in Immune Response and Regulation (eBook, ePUB)

• Format: ePub

Produktbeschreibung

G Protein-Coupled Receptors in Immune Response and Regulation, Volume 136 presents emerging concepts related to the role of GPCRs in immune response and regulation. Users will find updated chapters on a variety of topics, including Beta-adrenergic signaling in the onset and progression of asthma, the Emerging roles of Regulators of G protein signaling (RGS) proteins in the immune system, information on Kinin receptors in immune response and pathogenic infections, and sections on GPCR signaling in C. elegans and its implications in immune response, GPCR Kinases in Inflammatory response and signaling, and GRK2 in Inflammation: Regulation of T cell receptors and IgE signaling. Chapters in this book discuss not only the well-known aspects of GPCR signaling in immunology, but also presents many emerging paradigms that have not yet been reported in classical textbooks. Each chapter presents a forward-looking discussion, providing a glimpse of the tremendous potential associated with the specific receptor systems discussed. - Brings together contributions from leading experts in the area of GPCR biology - Discusses current paradigms and the future potential of understanding GPCR signaling in immune response and regulation - Presents the first of its kind book to focus on specific GPCR systems in various aspects of immunology, all brought together in one volume

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 398
• Erscheinungstermin: 23. September 2017
• Englisch
• ISBN-13: 9780128124048
• Artikelnr.: 49240673

Autorenporträt

Dr. Arun K. Shukla is a world leader in the field of GPCR biology and he is currently a Professor in the Department of Biological Sciences and Bioengineering at the Institute of Technology, Kanpur in India. Dr. Shukla's research program is focused on understanding the structure, function and regulation of G protein-coupled receptors with a long-term of designing novel therapeutics with minimized side-effects.

Inhaltsangabe

1. B2-Adrenoceptor Function in Asthma
Yassine Amrani and Peter Bradding
2. G Protein-Coupled Kinin Receptors and Immunity Against Pathogens
Julio Scharfstein, Pablo I.P. Ramos and Manoel Barral-Netto
3. P2Y Receptors in Immune Response and Inflammation
Diana Le Duc, Angela Schulz, Vera Lede, Annelie Schulze, Doreen Thor, Antje Brüser and Torsten Schöneberg
4. Emerging Roles for MAS-Related G Protein-Coupled Receptor-X2 on Host Defense Peptide, Opioid, and Neuropeptide-Mediated Inflammatory Reactions
Hydar Ali
5. Adhesion GPCRs in Regulating Immune Responses and Inflammation
Hsi-Hsien Lin, Cheng-Chih Hsiao, Caroline Pabst, Josée Hébert, Torsten Schöneberg and Jörg Hamann
6. GPCR Signaling in C. elegans and Its Implications in Immune Response
Anjali Gupta and Varsha Singh
7. G Protein-Coupled Receptor Kinases in the Inflammatory Response and Signaling
Michael D. Steury, Laura R. McCabe and Narayanan Parameswaran
8. Canonical and Noncanonical Signaling Roles of ?-Arrestins in Inflammation and Immunity
Mohammad M. Ahmadzai, David Broadbent, Christopher Occhiuto, Canchai Yang, Rupali Das and Hariharan Subramanian
9. Emerging Roles of Regulators of G Protein Signaling (RGS) Proteins in the Immune System
Kirk M. Druey
10. Roles of NHERF Family of PDZ-Binding Proteins in Regulating GPCR Functions
David Broadbent, Mohammad M. Ahmadzai, Ananth K. Kammala, Canchai Yang, Christopher Occhiuto, Rupali Das and Hariharan Subramanian