Veli Makinen, Djamal Belazzougui, Fabio Cunial, Alexandru I. Tomescu

Genome-Scale Algorithm Design (eBook, PDF)

Bioinformatics in the Era of High-Throughput Sequencing

• Format: PDF

Produktdetails

• Verlag: Cambridge University Press
• Erscheinungstermin: 12. Oktober 2023
• Englisch
• ISBN-13: 9781009341219
• Artikelnr.: 70909005

Autorenporträt

Veli Mäkinen is Professor of Computer Science at the University of Helsinki, where he leads a research team on genome-scale algorithmics. He has taught advanced courses on algorithm design and analysis, string processing, data compression, and algorithmic genome analysis, as well as introductory courses on bioinformatics.

Inhaltsangabe

Part I. Preliminaries: 1. Molecular biology and high-throughput sequencing
2. Algorithm design
3. Data structures
4. Graphs
5. Network flows
Part II. Fundamentals of Biological Sequence Analysis: 6. Alignments
7. Hidden Markov models
Part III. Genome-Scale Index Structures: 8. Classical indexes
9. Burrows-Wheeler indexes
Part IV. Genome-Scale Algorithms: 10. Alignment-based genome analysis
11. Alignment-free genome analysis and comparison
12. Compression of genome collections
13. Fragment assembly
Part V. Applications: 14. Haplotype analysis
15. Pangenomics
16. Transcriptomics
17. Metagenomics
References
Index.