Eugenia Wang, Huber R. Warner

Growth Control During Cell Aging (eBook, ePUB)

• Format: ePub

Produktbeschreibung

The purpose of this book is to provide information on senescent cells and why they are prevented from multiplying via cell division. It includes main sections on the nature of Go/1 transition, factors promoting the cell cycle traverse and avoiding the Go/1 arrest, and negative factors arresting the cell cycle traverse and promoting the stay in the Go/1 stage. Filled with illustrations and explanations, it collectively presents the mechanisms that control the cellular aging process. This reference is a must for anyone with special interests in the biological community, and specifically the field of gerontology.

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Produktdetails

• Verlag: Taylor & Francis eBooks
• Seitenzahl: 280
• Erscheinungstermin: 11. August 2020
• Englisch
• ISBN-13: 9781000141511
• Artikelnr.: 59895505

Autorenporträt

Eugenia Wang and Huber R. Warner

Inhaltsangabe

INTRODUCTION. POSITIVE CONTROL of CELL PROLIFERATION. The Regulation of
Cell Senescence. Expression of Growth-Related Genes in Senescent Human
Diploid Fibroblasts. Changes in Gene Expression during
Senescence/Immortalization of Mouse Embryo Fibroblasts. Nuclear
Responsiveness to Intracellular Signals in Normal and Senescent
Lymphocytes. Activation Defects in T Cells from Old Mice. Age-Re-lated
Differences in DNA Polymerase Alpha Specific Activity: Potential for
Interaction in DNA Repair. Characterization of Proliferating Cell Nuclear
Antigen (PCNA), or Cyclin, as a Cellular Marker for S-Phase Cells..
NEGATIVE CONTROL of CELL PROLIFERATION. Cellular Senescence: The Result of
a Genetic Program. Inhibitors of DNA Synthesis in Senescent and Quiescent
Human Diploid Fibroblasts. Growth Control in Cultured 3T3 Fibroblasts:
Molecular Properties of a Growth Regulatory Factor Isolated from
Conditioned Medium. Programmed Gene Expressions Suggest Multiple Blocks to
Replication during Cell Aging. GENERAL RELATED SUBJECTS. A Potential Role
for Interspersed Repetitive Sequence Elements in Negative Growth
Regulation. DNA Methylation, Maintenance CpG-Methylase, and Senescence.
Finite Proliferative Capacity of Syrian Hamster Fetal and Adult Fibroblasts
In Vitro: A Model System for the Analysis of the Cellular Basis of Aging.
Cellular Factors Related to Cessation of Proliferation and Differentiation.
Control of Muscle Differentiation by Mitogen: A Rationale for Multiple
Restriction Points in the Cell Cycle. SUMMARY. Index.