Handbook of Molecular Force Spectroscopy (eBook, PDF)

Redaktion: Noy, Aleksandr

• Format: PDF

Produktbeschreibung

This volume presents a review of modern force spectroscopy, including fundamentals of intermolecular forces, technical aspects of the force measurements, and practical applications. The Handbook begins with a review of fundamental physics of loading single and multiple chemical bonds on the nanometer scale. It contains a discussion of thermodynamic and kinetic models of binding forces and dissipation effects in nanoscale molecular contacts, covers practical aspects of modern single-molecule level techniques, and concludes with applications of force spectroscopy to chemical and biological processes. Computer modeling of force spectroscopy experiments is also addressed.

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Produktdetails

• Verlag: Springer US
• Seitenzahl: 300
• Erscheinungstermin: 3. Dezember 2007
• Englisch
• ISBN-13: 9780387499895
• Artikelnr.: 37288281

Inhaltsangabe

Surface force apparatus measurements of molecular forces in biological adhesion
(Deborah Leckband, Univ. of Illinois, Urbana-Champaign).- Force spectroscopy with optical and magnetic tweezers (Richard Conroy, Harvard University).- Chemical Force Microscopy 1: Nanoscale probing of fundamental chemical interactions (Aleksandr Noy, LLNL, Dmitry V. Vezenov, Harvard University, and Charles M. Lieber, Harvard University).- Chemical Force Microscopy 2: Interactions in complex molecular assemblies (Dmitry V. Vezenov, Harvard University, Aleksandr Noy, LLNL, and Charles M. Lieber, Harvard University).- Dynamic force spectroscopy with the atomic force microscope (Phil Williams, University of Nottingham).- Simulation in force spectroscopy (David L. Patrick, Western Washington University).- Probe tip functionalization: applications to chemical force microscopy (Craig D. Blanchard, Albert Loui, and Timothy V. Ratto, LLNL).- The dynamical response of proteins under force.- (Kirstine L. Anderson, Sheena E. Radford, D. Alastair Smith, and David J. Brockwell, University of Leeds).- Counting and breaking single bonds: Dynamic force spectroscopy in tethered single molecule systems (Todd A. Sulchek, Raymond W. Friddle, and Aleksandr Noy, LLNL).- Direct mapping of intermolecular interaction potentials (Paul D. Ashby, MIT)

Rezensionen

From the reviews: "A series of ten chapters on various aspects of force spectroscopy, each written by an expert in the field. This book ... aims 'to present a series of topics that discuss fundamental concepts and basic methodology used to perform and understand force spectroscopy experiments and illustrate them using examples from current and past research.' This work would represent a good introduction to the area for anyone wishing to know more about this increasingly important subject. Summing Up: Highly recommended. Upper-division undergraduate through professional collections." (A. Fry, CHOICE, Vol. 45 (10), June, 2008) "A broad overview of core principles of force spectroscopy is of considerable utility and timeliness. Aleksandr Noy ... has done an admirable job of assembling such an overview as well as providing insight into likely new directions of research. ... a timely and useful summary of fundamental aspects of molecular force spectroscopy, and I believe it would make a worthwhile addition to any good scientific library. New research groups that are entering this field would be well advised to study this handbook ... ." (Matthew F. Paige, Journal of the American Chemical Society, Vol. 130 (26), 2008) "In this nicely produced volume, one of the subject's key architects and proponents presents an extremely timely and effective summary of the field. The content is well judged ... . Overall, this book represents a very worthwhile and up-to-date introduction to an exciting new field of optics." (Optics and Photonics News, July/August, 2008)