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High Platelets
Today I received a laboratory report of a patient who had 1,093,000 platelets per micro liter which is well above the normal maximal level of 450,000 platelets.
This is the first time that I have received such a high level of platelets in my 41 years of medical practice.
I probably have to do further investigations on him before I can come to a conclusive diagnosis.
However with such a high platelet count I probably should be worried about the coagulability of his blood and may need to give him a low dose of aspirin to prevent blood clot in his blood vessels.
A
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Produktbeschreibung
High Platelets
Today I received a laboratory report of a patient who had 1,093,000 platelets per micro liter which is well above the normal maximal level of 450,000 platelets.
This is the first time that I have received such a high level of platelets in my 41 years of medical practice.
I probably have to do further investigations on him before I can come to a conclusive diagnosis.
However with such a high platelet count I probably should be worried about the coagulability of his blood and may need to give him a low dose of aspirin to prevent blood clot in his blood vessels.
A high platelet count is 450,000 per micro liter or above
A higher-than-normal number of platelets are called thrombocytosis or thrombocythemia.
It means the body is making too many platelets.
Causes may include:
1. A type of anemia in which red blood cells in the blood are destroyed earlier than normal (hemolytic anemia)
2. Anemia due to low iron
3. After certain infections, major surgery or trauma, or allergic reactions
4. Cancer
5. Certain medicines
6. Bone marrow disease called polycythemia vera
7. Bone marrow making too many platelets without a known cause (primary thrombocytosis)
8. Recent spleen removal
Some people with high platelet counts may be at risk of forming blood clots.
Blood clots can lead to serious medical problems
Thrombocytosis or thrombocythemia is defined as a platelet count above the upper limit of the normal range (450 x 109 per micro liter in adults).
The term thrombocythemia (or primary thrombocytosis) is preferred when the cause of a high platelet count is not known.
When another disease or condition causes a high platelet count, the term thrombocytosis (or secondary thrombocytosis) is preferred.
It is important to distinguish between true hematological disease causing primary thrombocytosis and secondary or reactive thrombocytosis caused by a physiological response to a primary problem.
There are a number of hematological diseases causing primary thrombocytosis.
Primary thrombocytosis is a chronic myeloproliferative disorder.
However, there are other hematological diseases which can cause primary thrombocytosis, including
1. Myeloproliferative neoplasms (MPNs),
2. Myelodysplastic syndromes (MDS)
3. Overlap syndromes.
MPNs such as primary thrombocytosis (essential thrombocythemia), polycythemia vera and myelofibrosis are Philadelphia-negative clonal disorders of the bone marrow.
Types of Thrombocytosis
There are broadly two types of thrombocytosis:
Hematological disease such as primary thrombocytosis
Primary thrombocytosis (also referred to as essential thrombocytosis, essential thrombocythemia and primary thrombocythemia) is due to a failure to regulate the production of platelets (autonomous production) and is a feature of a number of myeloproliferative disorders.
Features are a platelet count greater than 600 x 109 per micro liter, megakaryocyte hyperplasia, splenomegaly and a tendency to both thrombosis and hemorrhage.
Platelet survival is normal but function is not.
Other hematological diseases which cause primary thrombocytosis are myeloproliferative, myelodysplastic or a combination of both.
It includes some leukemia.
With primary thrombocytosis, a high platelet count may occur alone or with other blood cell disorders.
Secondary or reactive thrombocytosis
This can be secondary to a number of conditions.
When another disease or condition produces a high platelet count, the term "thrombocytosis" is preferred.
This condition often is called secondary or reactive thrombocytosis.
It is an exaggerated physiological response to a primary problem, such as an infection.
TABLE OF CONTENT
Introduction
Chapter 1 High Platelets
Chapter 2 Causes
Chapter 3 Symptoms
Chapter 4 Diagnosis
Chapter 5 Treatment
Chapter 6 Prognosis...


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Autorenporträt
Dr. Kenneth Kee is a well-known medical doctor from Singapore who has been practicing medicine since 1972.
He graduated from the University of Singapore and furthered his studies with a Master of Science in Health Management in 1991, followed by a Ph.D. in Healthcare Administration in 1993.
Dr. Kee established Kee Clinic in 1974, located in the Holland Drive area of Singapore. The clinic has been a prominent feature of the community, offering general medical services for 5 decades.
Dr Kee also served his country Singapore as a national service police Inspector at night from 1975 to 1985 while working at his clinic during the day.
He had served as a police guard to the Woodland Petroleum Tanks at night during the Indonesian Confrontation period, took part in police rounds at night in the Beach Road area and taught First aid and emergency resuscitation to Police recruits.
He received the Singapore Police Bicentennial 2020 Medallion on 1st March 2024 as recognition for his work in the Singapore Police.
Even as he grew older, Dr. Kee continued to work actively in his clinic, although he eventually reduced his consultation hours.
Beyond his medical career, Dr. Kee is also an author.
He started writing about medical conditions in 2007, using blogs and other online platforms to share his knowledge with a broader audience.
Over time, he published various books, many of which provide simple and accessible guides to different health conditions.
His works include "A Family Doctor's Tale," "My Personal Singapore History," and numerous medical guides, available through platforms like Amazon.
His books often combine his personal experiences as a family doctor with insights into Singapore's healthcare system and history.
Dr. Kee has written extensively on health topics, contributing to both medical literature and general knowledge resources.

Dr. Kenneth Kee has written numerous books, primarily focused on health education and personal experiences as a family doctor. Some of his notable titles include:
"A Family Doctor's Tale"
This book is a blend of Dr. Kee's personal experiences and his reflections on being a family doctor in Singapore. It's a great choice if you're looking for a narrative that combines both medical knowledge and human stories.
"Specialized Medical Conditions"
Books like **"Congestive Heart Failure: Diagnosis and Treatment"** focus on specific conditions, offering in-dept...