Human Reproductive and Prenatal Genetics (eBook, ePUB)

Redaktion: Leung, Peter C. K.; Qiao, Jie

• Format: ePub

Produktbeschreibung

Human Reproductive and Prenatal Genetics, Second Edition provides application-driven coverage of key topics in human reproductive and prenatal genetics, including genetic control underlying the development of the reproductive tracts and gametogenesis, the genetics of fertilization and implantation, the genetic basis of female and male infertility, as well as genetic and epigenetic aspects of assisted reproduction. Also examined are the genetics and epigenetics of the placenta in normal and abnormal pregnancy, preimplantation genetic diagnosis and screening, and cutting-edge advances in noninvasive prenatal screening, prenatal genetic counseling, and bioethical and medicolegal aspects of relevance in the lab and clinic.

This new edition has been fully revised to address new and evolving technologies in human reproductive genetics, with new chapters added on chromatin landscapes and sex determination, genetic alterations of placental development and preeclampsia, metabolism and inflammation in PCOS, pre-implantational genetic testing, maternal genetic disorders, bioethics, and future applications.

• Features chapter contributions from leading international scientists and clinicians
• Provides in-depth coverage of key topics in human reproductive and prenatal genetics, including genetic controls, fertilization, placental development, embryo implantation, in vitro culture of the human embryo for the study of post-implantation development, and more
• Identifies how researchers and clinicians can implement the latest genetic, epigenetic, and -omics-based approaches
• Includes all new chapters on evolving technologies and recent genetic discoveries of relevance to reproductive medicine

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 928
• Erscheinungstermin: 22. März 2023
• Englisch
• ISBN-13: 9780323913812
• Artikelnr.: 67658841

Inhaltsangabe

Section I: Reproductive tract development and gametogenesis 1. Developmental genetics of the male reproductive system Marisol O'Neill
Victor A. Ruthig
Meade Haller
Boryana Zhelyazkova
Jeffrey T. White
Nannan Thirumavalavan
and Dolores J. Lamb 2. Developmental genetics of the female reproductive tract Jessica Garcia de Paredes
Michael Strug
Jordan Gosnell
Marcos Cordoba
and Jose M. Teixeira 3. Genetics and genomics of early gonad development Fanghong Ou
Zhangting Wang
Jinyue Liao
Hoi-Ching Suen
Kai Kei Miu
and Wai-Yee Chan 4. Effects of aging on sperm chromatin Heather E. Fice and Bernard Robaire 5. In vitro spermatogenesis from pluripotent stem cells Jin Du
Qing-Qin Gao
Cheng Huang
Hai-Ping Jiang
Mo-Yu Dai
Yu-Fei Li
Jun Wu
and Qi Zhou 6. The molecular genetics of oogenesis Fan Zhai
Xinyi Ma
Liying Yan
and Jie Qiao 7. Growth of the mammalian oocyte: Focus on intercellular contact and communication Hugh J. Clarke 8. In vitro activation of ovarian follicles Kazuhiro Kawamura Section II: Embryo implantation
placenta development and pregnancy 9. Interaction of sperm and embryo with the female reproductive tract Yin Lau Lee
Andy Chun Hang Chen
and William Shu Biu Yeung 10. MicroRNAs in gametes and preimplantation embryos: Clinical implications Allison Tscherner
Nicholas Werry
Leanne Stalker
and Jonathan LaMarre 11. Epigenetic modifications in the human placenta Wendy P. Robinson
Maria S. Pen¿ aherrera
Chaini Konwar
Victor Yuan
and Samantha L. Wilson 12. In vitro models of human blastocysts and early embryogenesis Jia Ping Tan
Xiaodong Liu
and Jose M. Polo 13. microRNAs in pregnancy: Implications for basic research and clinical management Peng Xu
Xuan Shao
Ming Liu
and Yan-Ling Wang 14. Human X-chromosome inactivation: Complexity and clinical implications Maria Jose Navarro-Cobos
Karanveer Bhangu
and Carolyn J. Brown 15. The intergenerational effects on fetal programming He-Feng Huang
Guo-Lian Ding
Xin-Yuan Li
Xin-Mei Liu
and Zi-Ru Jiang Section III: Infertility and assisted reproductive technology 16. Theoretical and experimental strategies for preservation and restoration of male fertility Ali Honaramooz 17. Update on the genetics and genomics of premature ovarian insufficiency Elena J. Tucker
Sylvie Jaillard
and Andrew H. Sinclair 18. Premature ovarian insufficiency Yingying Qin
Ting Guo
Shidou Zhao
and Zi-Jiang Chen 19. Genetics of polycystic ovary syndrome Tristan Hardy
Alice P. Rogers
and Robert J. Norman 20. Developmental origins and genetic basis of polycystic ovary syndrome T.M. Barber and S. Franks 21. Genetic basis of metabolism and inflammation in PCOS Yanli Pang
Yue Zhao
and Jie Qiao 22. Genetics and genomics of recurrent pregnancy loss Laura Kasak
Kristiina Rull
and Maris Laan 23. Genetics and genomics of endometriosis Linda C. Giudice
Richard O. Burney
Christian M. Becker
Stacey A. Missmer
Grant Montgomery
Nilufer Rahmioglu
Peter A.W. Rogers
and Krina Zondervan 24. Human genetics and assisted reproduction in endometriosis Ya-Ching Chou
Chien-Wen Chen
Endah Rahmawati
Guan-Lin Lai
Yun-Yi Ma
Yi-Xuan Lee
Ming-Jer Chen
and Chii-Ruey Tzeng 25. Uterus transplantation as an infertility treatment Mats Brannstrom
Ali Khatibi
Ghada Hussein
and Pernilla Dahm-KEURahler 26. Impacts of COVID-19 on reproductive health and prenatal genetics Peng Yuan
Zhiqiang Yan
Wei Wang
Yao Li
Qilong He
Fan Zhai
Liying Yan
and Jie Qiao Section IV: Preimplantation/prenatal genetic diagnosis and screening 27. Genomics in reproductive medicine: Current and future applications Maurizio Poli and Antonio Capalbo 28. Molecular cytogenomics of human genetic disorders Zirui Dong
Kwong Wai Choy
and Cynthia C. Morton 29. Next-generation sequencing for gene panels
clinical exome
and whole-genome analysis Matthew A. Shanahan
Liesbeth Vossaert
and Ignatia B. Van den Veyver 30. Chromosomal microarrays and next-generation sequencing for diagnosis of fetal abnormalities Brynn Levy
Melissa Stosic
Jessica Giordano
Ronald Wapner
and Vimla Aggarwal 31. Noninvasive prenatal testing for genetic diseases Stephanie C.Y. Yu
Jason C.H. Tsang
and Y.M. Dennis Lo 32. Noninvasive prenatal testing/screening by circulating cell-free DNA Margot van Riel
Kate Stanley
and Joris R. Vermeesch 33. Application of new technologies in embryos: From gene editing to synthetic embryos M. Martin-Inaraja
I. Romayor
L. Herrera
N. Montserrat
and C. Eguizabal