Kenneth Kee

Hypopituitarism, A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions (eBook, ePUB)

• Format: ePub

Produktbeschreibung

Hypopituitarism is a medical disorder in which the pituitary gland does not normally produce usual amounts of some or all of its eight hormones.
Hypopituitarism is due to an inadequate production of hypothalamic-releasing hormones or due to an inability of the pituitary gland to secrete hormones.
Hypopituitarism is typically chronic and lifelong unless successful surgery or medicinal therapy of the underlying cause can restore pituitary function.
Causes
In hypopituitarism, there is a loss or decrease of one or more pituitary hormones.
Decrease of a hormone results in loss of function in the gland and the hormonal regulation.
Loss of TSH results in loss of function of the thyroid gland.
1.Brain surgery
2.Brain tumor
3.Head trauma
4.Infections or inflammation of the brain and the tissues that support the brain
5.Radiation therapy
6.Stroke
Sometimes, hypopituitarism is due to abnormal immune system or metabolic diseases, such as:
1. Hemochromatosis
2. Histiocytosis X
Symptoms
The patient presents with endocrine dysfunction:
A.Adrenocorticotrophic hormone (ACTH) deficiency:
1.Chronic: fatigue, pallor, anorexia, weight loss.
2.Acute: weakness, dizziness, nausea, vomiting, fever, shock.
3.Children: delayed puberty, failure to thrive.
4.Hypoglycemia, hypotension, anemia, lymphocytosis, hyponatremia.
B.Thyroid-stimulating hormone (TSH) deficiency:
1.Tiredness, cold intolerance, constipation, hair loss, dry skin, cognitive slowing.
2.Weight gain, bradycardia, hypotension.
3.Children: delayed development, growth restriction, intellectual impairment.
C Gonadotrophin deficiency:
1.Women: oligomenorrhea, loss of libido, dyspareunia, infertility, osteoporosis.
2.Men: loss of libido, loss of facial, scrotal, and body hair, mood impairment, reduced muscle mass, osteoporosis, anemia.
3.Children: delayed puberty.
D.Growth hormone deficiency:
1.Reduced muscle mass and strength, visceral obesity, impairment of attention, memory.
2.Dyslipidemia, premature atherosclerosis.
3.Children: growth restriction.
E.Antidiuretic hormone deficiency:
1.Polyuria, polydipsia.
2.Reduced urine osmolality, hypernatremia.
3.May also present with features due to the underlying cause:
a.Space-occupying lesion: headaches or visual field deficits.
b.Large lesions affecting the hypothalamus: polydipsia and inadequate secretion.
Diagnosis:
To diagnose hypopituitarism, there must be low hormonal amounts from the pituitary gland.
1.Serum ACTH
2.Serum cortisol
3.Serum estradiol
4.Serum follicle stimulating hormone
5.Serum insulin-like growth factor 1
6.Serum luteinizing hormone
7.Serum testosterone level
8.Serum thyroid stimulating hormone
9.Thyroid hormone
10.Brain CT scan
11.Pituitary MRI
Treatment
Acute resuscitation, such as intravenous fluids, may be needed
If hypopituitarism has been caused by a tumor, pituitary function may be returned to normal after successful surgical or medical removal of the lesion.
Surgical:
In pituitary stroke or coma, immediate operative decompression may be life-saving.
Removal of macroadenomas may be needed if they do not respond to medical therapy.
If hypopituitarism is caused by a tumor, you may require surgery to excise the tumor.
Radiation therapy may also be needed
Medical care consists of hormone replacement as appropriate and treatment of the underlying cause.
The patient will need lifelong hormone medicines to replace hormones that are no longer made by glands under the regulation of hormones from the pituitary gland.
1.Corticosteroids (cortisol)
2.Growth hormone
3.Sex hormones (testosterone for men and estrogen for women)
4.Thyroid hormone

TABLE OF CONTENT
Introduction
Chapter 1 Hypopituitarism
Chapter 2 Causes
Chapter 3 Symptoms
C...

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Produktdetails

• Verlag: Kenneth Kee
• Erscheinungstermin: 17. April 2018
• Englisch
• ISBN-13: 9781370212897
• Artikelnr.: 52435566

Autorenporträt

Dr. Kenneth Kee is a well-known medical doctor from Singapore who has been practicing medicine since 1972.
He graduated from the University of Singapore and furthered his studies with a Master of Science in Health Management in 1991, followed by a Ph.D. in Healthcare Administration in 1993.
Dr. Kee established Kee Clinic in 1974, located in the Holland Drive area of Singapore. The clinic has been a prominent feature of the community, offering general medical services for 5 decades.
Dr Kee also served his country Singapore as a national service police Inspector at night from 1975 to 1985 while working at his clinic during the day.
He had served as a police guard to the Woodland Petroleum Tanks at night during the Indonesian Confrontation period, took part in police rounds at night in the Beach Road area and taught First aid and emergency resuscitation to Police recruits.
He received the Singapore Police Bicentennial 2020 Medallion on 1st March 2024 as recognition for his work in the Singapore Police.
Even as he grew older, Dr. Kee continued to work actively in his clinic, although he eventually reduced his consultation hours.
Beyond his medical career, Dr. Kee is also an author.
He started writing about medical conditions in 2007, using blogs and other online platforms to share his knowledge with a broader audience.
Over time, he published various books, many of which provide simple and accessible guides to different health conditions.
His works include "A Family Doctor's Tale," "My Personal Singapore History," and numerous medical guides, available through platforms like Amazon.
His books often combine his personal experiences as a family doctor with insights into Singapore's healthcare system and history.
Dr. Kee has written extensively on health topics, contributing to both medical literature and general knowledge resources.

Dr. Kenneth Kee has written numerous books, primarily focused on health education and personal experiences as a family doctor. Some of his notable titles include:
"A Family Doctor's Tale"
This book is a blend of Dr. Kee's personal experiences and his reflections on being a family doctor in Singapore. It's a great choice if you're looking for a narrative that combines both medical knowledge and human stories.
"Specialized Medical Conditions"
Books like **"Congestive Heart Failure: Diagnosis and Treatment"** focus on specific conditions, offering in-dept...