Mechanosensitive Ion Channels (eBook, PDF)

Redaktion: Kamkin, Andre; Kiseleva, Irina

• Format: PDF

Produktbeschreibung

This book explores the latest data dealing with mechanosensitive channels research results. It was compiled by a group of internationally recognized scientists leading in the field of mechanosensitive ion channels or mechanically gated channels and signaling cascades research. Key problems of cell mechanobiology are also discussed. As a whole, the volume dwells on the major issues of mechanical stress influencing the ion channels and intracellular signaling pathways.

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Produktdetails

• Verlag: Springer Netherlands
• Seitenzahl: 382
• Erscheinungstermin: 6. Oktober 2007
• Englisch
• ISBN-13: 9781402064265
• Artikelnr.: 37346030

Inhaltsangabe

Foreword I.- Foreword II.- Editorial Mechanically gated channels and mechanosensitive channels.- Part I. Mechanosensitive Channels.- Experimental methods of studying of mechanosensitive channels and possible errors in data interpretation.- The role of lipid bilayer mechanics in mechanosensation.- Mechanosensitive channels gated by membrane tension: bacteria and beyond.- Computational approaches in studies of bacterial mechanosensitive channels.- Mechanosensory transduction in the nematode Caenorhabditis elegans.- Mechanosensitive ion channels in odontoblasts.- Potassium ion channels in articular chondrocytes: putative roles in mechanotransduction, metabolic regulation and cell proliferation.- Osmotransduction through volume-sensitive Cl - channels.- Mechanosensitive channel TRPV4. A micro-machine converting physical force into an ion flow. Part II Mechanosensitive Signaling Cascades.- Mechanosensitive purinergic calcium signalling in articular chondrocytes.- Signal transduction pathways involved in mechanotransduction in osteoblastic and mesenchymal stem cells.- Caveolae: Co-ordinating centres for mechanotransduction in the heart?- Multimodal activation and regulation of neuronal mechanosensitive cation channels.- Rregulation of intracellular signal transduction pathways by mechanosensitive ion channels. Part III. Cell Mechanobiology.- The effects of mechanical stimulation on vertebrate hearts: a question of class.- Mechanobiology of fibroblasts