Microarray Innovations (eBook, PDF)

Technology and Experimentation
Redaktion: Hardiman, Gary

• Format: PDF

Produktbeschreibung

In recent years, high-density DNA microarrays have revolutionized biomedical research and drug discovery efforts by the pharmaceutical industry. Their efficacy in identifying and prioritizing drug targets based on their ability to confirm a large number of gene expression measurements in parallel has become a key element in drug discovery. Microarr

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Produktdetails

• Verlag: Taylor & Francis eBooks
• Seitenzahl: 314
• Erscheinungstermin: 2. April 2009
• Englisch
• ISBN-13: 9781420094510
• Artikelnr.: 57533884

Autorenporträt

Gary Hardiman

Inhaltsangabe

Introduction to Gene Expression Profiling with DNA Microarray Technology.
Introduction to Large-Scale Gene Expression Data Analysis. The Statistical
Design and Analysis of Gene Expression Data. Laboratory Automation for
Microarray Experimentation. How to Evaluate a Microarray Scanner. The Role
of Substrates in Microarray Experimentation and How to Choose the Correct
Coating for Microarraying. Towards Highly Efficient Automated
Hybridizations. Characterization of Microarray Hybridization Stoichiometry.
Data Normalization Selection. Methods for Assessing Microarray Performance.
Comparison of Different Normalization Methods for Applied Biosystems
Expression Array System. A Systematic Comparison of Gene Expression
Measurements Across Different Hybridization-Based Technologies. DNA
Methylation Arrays: Methods and Analysis. Electronic Microarrays: Progress
toward DNA Diagnostics. New Applications for Microarrays. Development of an
Oligonucleotide Microarray for Mutational Analysis Using Single or Multiple
Sample Hybridization. Development of an Integrated Molecular Diagnostic
Test to Identify Respiratory Viruses. Microarrays in Neuroscience.
Optimization of Protein Array Fabrication for Establishing High Throughput
Ultra-Sensitive Microarray Assays for Cancer Research. Index.