Microbial Cell Factories Engineering for Production of Biomolecules (eBook, ePUB)

Redaktion: Singh, Vijai

• Format: ePub

Produktbeschreibung

Microbial Cell Factories Engineering for Production of Biomolecules presents a compilation of chapters written by eminent scientists worldwide. Sections cover major tools and technologies for DNA synthesis, design of biosynthetic pathways, synthetic biology tools, biosensors, cell-free systems, computer-aided design, OMICS tools, CRISPR/Cas systems, and many more. Although it is not easy to find relevant information collated in a single volume, the book covers the production of a wide range of biomolecules from several MCFs, including Escherichia coli, Bacillus subtilis, Pseudomonas putida, Streptomyces, Corynebacterium, Cyanobacteria, Saccharomyces cerevisiae, Pichia pastoris and Yarrowia lipolytica, and algae, among many others.

This will be an excellent platform from which scientific knowledge can grow and widen in MCF engineering research for the production of biomolecules. Needless to say, the book is a valuable source of information not only for researchers designing cell factories, but also for students, metabolic engineers, synthetic biologists, genome engineers, industrialists, stakeholders and policymakers interested in harnessing the potential of MCFs in several fields.

• Offers basic understanding and a clear picture of various MCFs
• Explains several tools and technologies, including DNA synthesis, synthetic biology tools, genome editing, biosensors, computer-aided design, and OMICS tools, among others
• Harnesses the potential of engineered MCFs to produce a wide range of biomolecules for industrial, therapeutic, pharmaceutical, nutraceutical and biotechnological applications
• Highlights the advances, challenges, and future opportunities in designing MCFs

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 488
• Erscheinungstermin: 13. Februar 2021
• Englisch
• ISBN-13: 9780128214787
• Artikelnr.: 61690513

Inhaltsangabe

1. Advances and opportunity in design of microbial cell factories for
production of biomolecules 2. Advances in long DNA synthesis 3. Discovery
of enzymes responsible for cyclization and post-modification in
triterpenoid biosynthesis 4. Synthetic biology for metabolic engineering of
secondary metabolites 5. Synthetic biology design tools for metabolic
engineering 6. Metabolic engineering for microbial cell factories 7. CRISPR
based tools for microbial cell factories 8. Escherichia coli, the workhorse
cell factory for the production of chemicals 9. Bacillus subtilis based
microbial cell factories 10. Pseudomonas putida- based cell factories 11.
Streptomyces based cell factories for production of biomolecules and
bioactive metabolites 12. Corynebacterium glutamicum as a robust microbial
factory for production of value-added proteins and small molecules:
Fundamentals and applications 13. Production of high value-added chemicals
in engineering methylotrophic cell factories 14. Cyanobacteria based
microbial cell factories for production of industrial products 15.
Integrated omics perspective to understand the production of high-value
added biomolecules (HVABs) in microalgal cell factories 16. Saccharomyces
cerevisiae as a microbial cell factory 17. Pichia pastoris based microbial
cell factories 18. Yarrowia lipolytica engineering as a source of microbial
cell factories 19. Engineering of microbial cell factories for production
of plant-based natural products 20. Engineering of microbial cell factories
for Omic-guided production of medically important biomolecules 21. Advances
and applications of cell-free systems for metabolic production 22.
Microbial biosensors for discovery and engineering of enzymes and
metabolism 23. Manipulation of global regulators in Escherichia coli for
the synthesis of biotechnologically relevant products