Modeling Fragile X Syndrome (eBook, PDF)

Redaktion: Denman, Robert B.

• Format: PDF

Produktbeschreibung

Introduction.-Probing Astrocyte Function in Fragile X Syndrome.- Neural Stem Cells.- Fragile X Mental Retardation Protein (FMRP) and the Spinal Sensory System.- The Role of the Postsynaptic Density in the Pathology of the Fragile X Syndrome.- Behavior in a Drosophila model of Fragile X.- Molecular and Genetic Analysis of the Drosophila Model of Fragile X Syndrome.- Fragile X Mental Retardation Protein and Stem Cells.- Manipulating the Fragile X Mental Retardation Proteins in the Frog.- Exploring the Zebra finch Taeniopygia gutta as a Novel Animal Model for the Speech-language Deficit of Fragile X Syndrome.- Neuroendocrine Alterations in the Fragile X Mouse.- Taking STEPs forward to understanding Fragile X Syndrome.- Fmr-1 as an Offspring Genetic and a Maternal Environmental Factor in Neurodevelopmental Disease.- Mouse Models of the Fragile X Premutation and the Fragile X Associated Tremor/Ataxia Syndrome.- Clinical Aspects of the Fragile X Syndrome.- Fragile X Syndrome: A Psychiatric Perspective.- Fragile X Syndrome and Targeted Treatment Trials.- The Fragile X-associate Tremor Ataxia Syndrome.- Vignettes: Models in Absentia.

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Produktdetails

• Verlag: Springer Berlin Heidelberg
• Seitenzahl: 392
• Erscheinungstermin: 8. Juli 2014
• Englisch
• ISBN-13: 9783642216497
• Artikelnr.: 37372303

Inhaltsangabe

Introduction: Reminiscing on Models and Modeling.
Probing Astrocyte Function in Fragile X Syndrome.
Neural Stem Cells.
Fragile X Mental Retardation Protein (FMRP) and the Spinal Sensory System.
The role of the postsynaptic density in the pathology of the fragile X syndrome.
Behavior in a Drosophila model of Fragile X.
Molecular and Genetic Analysis of the Drosophila Model of Fragile X Syndrome.
Fragile X Mental Retardation Protein and Stem Cells.
Manipulating the Fragile Mental Retardation Proteins in the frog.
Exploring the zebra finch Taeniopygia guttata as a novel animal model for the speech
language deficit of fragile X syndrome.
Neuroendocrine alterations in the fragile X mouse.
Taking STEPs forward to understanding Fragile X Syndrome.
Fmr
1 as an offspring genetic and a maternal environmental factor in neurodevelopmental disease.
Mouse Models of the Fragile X Premutation and the Fragile X Associated Tremor/Ataxia Syndrome.
Clinical Aspects of the Fragile X Syndrome.
Fragile X Syndrome: A Psychiatric Perspective.
Fragile X Syndrome and Targeted Treatment Trials.
The Fragile X
associated Tremor Ataxia Syndrome.
Vignettes: Models in Absentia.