Kenneth Kee

Neurofibromatosis 1, A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions (eBook, ePUB)

• Format: ePub

Produktbeschreibung

Neurofibromatosis is a genetic medical disorder causing tumors in the skin, nervous system and skeleton.
The neurofibromatoses are autosomal dominant genetic disorders that consist of the rare diseases NF1, NF2, and schwannomatosis:
1. NF1 is the more common form of the neurofibromatoses.
Type 1 is caused by a defect in the gene, NF1, located at chromosome 17q11.2.
Neurofibromin, the gene product, is a widespread nervous system protein and is believed to act as a tumor suppressor.
Loss of neurofibromin results in a higher risk of forming benign and malignant tumors but effects of a mutation differ greatly between sufferers
It can occur at any age due to a range of mutations, differing penetration and mosaicism.
Watson's syndrome is the only subtype of NF1 to have a common phenotype in families and is typically featured by pulmonary stenosis, cognitive impairment, cafe au lait patches and few skin neurofibromas
In diagnosing NF1, a doctor looks for alterations in:
1. Skin appearance,
2. Tumors,
3. Bone abnormalities,
4. A parent, sibling or child with NF1.
Symptoms of NF1, which may be present at birth and nearly always by the time the child is 10 years old, are:
a. Light brown spots on the skin ("cafe-au-lait" spots),
b. Two or more growths on the iris of the eye,
c. A tumor on the optic nerve,
d. A larger than normal head circumference,
e. Abnormal development of the spine, a skull bone, or the tibia.
2. Type 2 is a central form with CNS tumors rather than skin lesions.
The tumors cause injury by pressure on the neighboring nerves.
CT or MRI of the brain or other involved sites may be needed.
Biopsy of asymptomatic skin neurofibromas need not be done for diagnostic purposes in patients with definite NF1.
There is no specific treatment for neurofibromatosis.
Tumors that cause pain or loss of function may be excised.
Tumors that have grown quickly should be excised promptly as they may become cancerous

TABLE OF CONTENT
Introduction
Chapter 1 Neurofibromatosis Type 1
Chapter 2 Causes
Chapter 3 Symptoms
Chapter 4 Diagnosis
Chapter 5 Treatment
Chapter 6 Prognosis
Chapter 7 Acoustic Neuroma
Chapter 8 Pheochromocytoma
Epilogue

---

Dieser Download kann aus rechtlichen Gründen nur mit Rechnungsadresse in A, B, CY, CZ, D, DK, EW, E, FIN, F, GR, H, IRL, I, LT, L, LR, M, NL, PL, P, R, S, SLO, SK ausgeliefert werden.

Produktdetails

• Verlag: Kenneth Kee
• Erscheinungstermin: 21. Oktober 2016
• Englisch
• ISBN-13: 9781370734450
• Artikelnr.: 75905578

Autorenporträt

Dr. Kenneth Kee is a well-known medical doctor from Singapore who has been practicing medicine since 1972.
He graduated from the University of Singapore and furthered his studies with a Master of Science in Health Management in 1991, followed by a Ph.D. in Healthcare Administration in 1993.
Dr. Kee established Kee Clinic in 1974, located in the Holland Drive area of Singapore. The clinic has been a prominent feature of the community, offering general medical services for 5 decades.
Dr Kee also served his country Singapore as a national service police Inspector at night from 1975 to 1985 while working at his clinic during the day.
He had served as a police guard to the Woodland Petroleum Tanks at night during the Indonesian Confrontation period, took part in police rounds at night in the Beach Road area and taught First aid and emergency resuscitation to Police recruits.
He received the Singapore Police Bicentennial 2020 Medallion on 1st March 2024 as recognition for his work in the Singapore Police.
Even as he grew older, Dr. Kee continued to work actively in his clinic, although he eventually reduced his consultation hours.
Beyond his medical career, Dr. Kee is also an author.
He started writing about medical conditions in 2007, using blogs and other online platforms to share his knowledge with a broader audience.
Over time, he published various books, many of which provide simple and accessible guides to different health conditions.
His works include "A Family Doctor's Tale," "My Personal Singapore History," and numerous medical guides, available through platforms like Amazon.
His books often combine his personal experiences as a family doctor with insights into Singapore's healthcare system and history.
Dr. Kee has written extensively on health topics, contributing to both medical literature and general knowledge resources.

Dr. Kenneth Kee has written numerous books, primarily focused on health education and personal experiences as a family doctor. Some of his notable titles include:
"A Family Doctor's Tale"
This book is a blend of Dr. Kee's personal experiences and his reflections on being a family doctor in Singapore. It's a great choice if you're looking for a narrative that combines both medical knowledge and human stories.
"Specialized Medical Conditions"
Books like **"Congestive Heart Failure: Diagnosis and Treatment"** focus on specific conditions, offering in-dept...