Kenneth Kee

Osler's Disease, A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions (eBook, ePUB)

• Format: ePub

Produktbeschreibung

This book describes Osler's Disease, Diagnosis and Treatment and Related Diseases
Osler disease is an inherited blood vessel disease that produces bleeding from the mucous membranes of the nose, gastrointestinal tract, lungs or urinary tract.
Patients may also have abnormal blood vessels that bleed in the brain.
Osler Disease or Osler-Weber-Rendu syndrome (OWR) is also called hereditary hemorrhagic telangiectasia (HHT).
It is a genetic blood vessel disorder that often causes excessive bleeding.
It was first thought to be a bleeding disease but this disorder is caused by problems with the blood vessels themselves.
People with OWR may have missing capillaries in some of their blood vessels.
These abnormal blood vessels are termed arteriovenous malformations (AVM).
Because there is nothing to reduce the pressure of the blood before it moves into the veins, people with OWR often have strained veins that may ultimately rupture.
When large AVMs arise, hemorrhages can happen.
Hemorrhages in these locations can become life-threatening:
1. The brain
2. The lungs
3. The liver
4. The gastrointestinal tract
People with OWR also have abnormal blood vessels termed "telangiectasias" near the skin and mucosal surfaces.
These blood vessels are swollen or widened and are often seen as small red dots on the skin surface.
The disorder can be found throughout the world.
The syndrome involves about one in 5,000 people.
Many people with the disorder do not know they have it, so this number may really be higher.
There is no gender difference.
People with OWR have an abnormal gene that causes their blood vessels to form imperfectly.
OWR is an autosomal dominant genetic disease.
This means that only one parent requires having the abnormal gene to pass it on to their children.
OWR does not pass over a generation.
The signs and symptoms may differ greatly between family members.
If the patient has OWR, it is possible that the child could have a milder or more serious course.
In very rare cases, a child can be born with OWR even when none of the parents has the syndrome.
This occurs when one of the genes that cause OWR forms mutation in an egg or sperm cell.
Symptoms
Symptoms of OWR and their severity differ widely, even among family members.
A frequent sign of OWR is a large red birthmark, occasionally called a port wine stain.
A port-wine stain is produced by a collection of dilated blood vessels, and it may become darker in color as the person grows older.
Telangiectasias (small dilated blood vessels) are another frequent symptom of OWR.
They are often small red dots and are susceptible to bleeding.
The marks may be observed in young children or not until after puberty.
Telangiectasias can emerge on the:
1. Face
2. Lips
3. Tongue
4. Ears
5. Fingertips
6. Whites of the eyes
7. Gastrointestinal system
AVMs can happen anywhere inside the body.
The most frequent sites are:
1. The nose
2. The lungs
3. The gastrointestinal tract
4. The liver
5. The brain
6. The spine
The most frequent symptom of OWR is nosebleeds produced by telangiectasias in the nose.
In fact, this is often the first symptom of OWR.
Nosebleeds may occur daily or as rarely as twice per year.
When AVMs develop in the lungs, they can involve lung function.
A person with a lung AVM may have shortness of breath.
Diagnosis:
Blood test can examine for anemia, or iron deficiency in the blood.
CT scan can reveal internal AVMs, such as in the lungs, liver, and brain
Treatment:
Treatment is to stop bleeding and replace blood loss
Iron supplements
Transfusion
Estrogen
Aminocaproic acid
Electrocautery and argon beam ablation
Laser cautery
Embolization of blood vessel
Surgery

TABLE OF CONTENT
Introduction...

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Produktdetails

• Verlag: Kenneth Kee
• Erscheinungstermin: 25. April 2019
• Englisch
• ISBN-13: 9780463418048
• Artikelnr.: 56498975

Autorenporträt

Dr. Kenneth Kee is a well-known medical doctor from Singapore who has been practicing medicine since 1972.
He graduated from the University of Singapore and furthered his studies with a Master of Science in Health Management in 1991, followed by a Ph.D. in Healthcare Administration in 1993.
Dr. Kee established Kee Clinic in 1974, located in the Holland Drive area of Singapore. The clinic has been a prominent feature of the community, offering general medical services for 5 decades.
Dr Kee also served his country Singapore as a national service police Inspector at night from 1975 to 1985 while working at his clinic during the day.
He had served as a police guard to the Woodland Petroleum Tanks at night during the Indonesian Confrontation period, took part in police rounds at night in the Beach Road area and taught First aid and emergency resuscitation to Police recruits.
He received the Singapore Police Bicentennial 2020 Medallion on 1st March 2024 as recognition for his work in the Singapore Police.
Even as he grew older, Dr. Kee continued to work actively in his clinic, although he eventually reduced his consultation hours.
Beyond his medical career, Dr. Kee is also an author.
He started writing about medical conditions in 2007, using blogs and other online platforms to share his knowledge with a broader audience.
Over time, he published various books, many of which provide simple and accessible guides to different health conditions.
His works include "A Family Doctor's Tale," "My Personal Singapore History," and numerous medical guides, available through platforms like Amazon.
His books often combine his personal experiences as a family doctor with insights into Singapore's healthcare system and history.
Dr. Kee has written extensively on health topics, contributing to both medical literature and general knowledge resources.

Dr. Kenneth Kee has written numerous books, primarily focused on health education and personal experiences as a family doctor. Some of his notable titles include:
"A Family Doctor's Tale"
This book is a blend of Dr. Kee's personal experiences and his reflections on being a family doctor in Singapore. It's a great choice if you're looking for a narrative that combines both medical knowledge and human stories.
"Specialized Medical Conditions"
Books like **"Congestive Heart Failure: Diagnosis and Treatment"** focus on specific conditions, offering in-dept...