Kenneth Kee

Ovarian Cancer, A Simple Guide To The Condition, Diagnosis, Treatment (eBook, ePUB)

• Format: ePub

Produktbeschreibung

Ovarian cancer is a malignant disease arising from the cells of the ovary.
It is the leading cause of death from gynecological cancer.
Epithelial cell tumors start from the cells on the surface of the ovaries.
These are the most common type of ovarian tumors.
Germ cell tumors start in the cells that produce the eggs.
They can either be benign or cancerous.
Causes:
a. Reproductive factors
The risk of epithelial ovarian cancer is increased in women who have not had children and possibly those with early menarche or late menopause.
Women who have been pregnant have a 50% decreased risk for developing ovarian cancer compared with nulliparous women.
Multiple pregnancies offer an increasingly protective effect.
Oral contraceptive use decreases the risk of ovarian cancer.
b. Genetic factors
Family history has an important role in the risk of developing ovarian cancer.
At least 2 syndromes of hereditary ovarian cancer are clearly identified, involving either
1. Disorders of the genes associated with breast cancer, BRCA1 and BRCA2, or
2. Genes within the Lynch II syndrome complex more rarely
Inheritance follows an autosomal dominant transmission.
Previous hormone therapy
Current users of hormones had incidence rate ratios for all ovarian cancers of 1.38 (95% confidence interval CI, 11.26-1.51) compared with women who never took hormone therapy.
Risk factors are
a. Increasing age.
b. Lifestyle.
Factors which increase the lifestyle risk include:
i. Smoking.
ii. Obesity.
There is evidence of increased risk in postmenopausal women who are overweight.
Presence of advanced ovarian cancer is often suspected on abdominal mass but can be confirmed only pathologically by removal of the ovaries or when disease is advanced, by sampling tissue or ascitic fluid.
Standard treatment is surgery (staging and optimal debulking) followed by adjuvant chemotherapy in most cases.
Even if optimal surgery is not possible, removing as much tumor as possible will provide significant palliation of symptoms.
Borderline lesions may be treated with conservative surgery.
In early disease, assessment of peritoneal cytology, hysterectomy, removal of ovaries and Fallopian tubes and infracolic omentectomy should be performed.
Management of early ovarian cancer in young women who desire future childbearing may be more conservative, i.e. a unilateral salpingo-oophorectomy and staging but the long-term safety is uncertain.
Treatment choice will depend on type of tumor and stage, and in partnership with the patient, who will need to be fully informed about prognosis.
Adjuvant platinum-based chemotherapy improves survival in early (Stage I/IIa) epithelial ovarian cancers
Chemotherapy is advised for all women with Stage II-IV disease following surgery.
New targeted treatments include:
Bavacizumab. This is a monoclonal antibody against vascular epithelial growth factor (VEGF).
This helps to prevent angiogenesis (the formation of new blood vessels), which is an important part of cancer growth.
Poly (ADP-ribose) polymerase (PARP) Inhibitors e.g., olaparib.

TABLE OF CONTENT
Introduction
Chapter 1 Ovarian Cancer
Chapter 2 Causes
Chapter 3 Symptoms
Chapter 4 Diagnosis
Chapter 5 Treatment
Chapter 6 Prognosis and Prevention
Chapter 7 Summary
Epilogue

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Produktdetails

• Verlag: Kenneth Kee
• Erscheinungstermin: 21. Oktober 2016
• Englisch
• ISBN-13: 9781370812271
• Artikelnr.: 48322243

Autorenporträt

Dr. Kenneth Kee is a well-known medical doctor from Singapore who has been practicing medicine since 1972.
He graduated from the University of Singapore and furthered his studies with a Master of Science in Health Management in 1991, followed by a Ph.D. in Healthcare Administration in 1993.
Dr. Kee established Kee Clinic in 1974, located in the Holland Drive area of Singapore. The clinic has been a prominent feature of the community, offering general medical services for 5 decades.
Dr Kee also served his country Singapore as a national service police Inspector at night from 1975 to 1985 while working at his clinic during the day.
He had served as a police guard to the Woodland Petroleum Tanks at night during the Indonesian Confrontation period, took part in police rounds at night in the Beach Road area and taught First aid and emergency resuscitation to Police recruits.
He received the Singapore Police Bicentennial 2020 Medallion on 1st March 2024 as recognition for his work in the Singapore Police.
Even as he grew older, Dr. Kee continued to work actively in his clinic, although he eventually reduced his consultation hours.
Beyond his medical career, Dr. Kee is also an author.
He started writing about medical conditions in 2007, using blogs and other online platforms to share his knowledge with a broader audience.
Over time, he published various books, many of which provide simple and accessible guides to different health conditions.
His works include "A Family Doctor's Tale," "My Personal Singapore History," and numerous medical guides, available through platforms like Amazon.
His books often combine his personal experiences as a family doctor with insights into Singapore's healthcare system and history.
Dr. Kee has written extensively on health topics, contributing to both medical literature and general knowledge resources.

Dr. Kenneth Kee has written numerous books, primarily focused on health education and personal experiences as a family doctor. Some of his notable titles include:
"A Family Doctor's Tale"
This book is a blend of Dr. Kee's personal experiences and his reflections on being a family doctor in Singapore. It's a great choice if you're looking for a narrative that combines both medical knowledge and human stories.
"Specialized Medical Conditions"
Books like **"Congestive Heart Failure: Diagnosis and Treatment"** focus on specific conditions, offering in-dept...