Phosphoinositides in Subcellular Targeting and Enzyme Activation (eBook, PDF)

Redaktion: Stenmark, Harald

• Format: PDF

Produktbeschreibung

Cells of the immune system are activated by a variety of stimuli that are derived from other cells, ingested material or from invading microorganisms. This issue of CTMI focuses on the mechanisms of phosphoinositide-mediated protein recruitment to intracellular membranes.

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Produktdetails

• Verlag: Springer Berlin Heidelberg
• Seitenzahl: 209
• Erscheinungstermin: 6. Dezember 2012
• Englisch
• ISBN-13: 9783642188053
• Artikelnr.: 53091382

Inhaltsangabe

List of Contents.- Phosphoinositide Involvement in Phagocytosis and Phagosome Maturation.- Regulation of Endocytosis by Phosphatidylinositol 4,5-Biphosphate and ENTH Proteins.- Membrane Targeting by Pleckstrin Homology Domains.- Protein Targeting to Endosomes and Phagosomes via FYVE and PX Domains.- Regulation of the Actin Cytoskeleton by PI(4,5)P2 and PI(3,4,5)P3.- Roles of PI3K in Neutrophil Function.- Nuclear Phosphoinositides and Their Functions.

Rezensionen

From the reviews:

"The book consists of seven chapters that focus on the various functions of PtdIns. ... summarises recent advances in the burgeoning field of inositol lipids and provides a snapshot of where the field stands in 2003. The field is moving rapidly but this volume will be a useful addition for many researchers who have only recently discovered that their favourite protein is regulated by PtdIns." (Shamshad Cockcroft, nature cell biology, Vol. 6 (6), June, 2004)