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Precision Medicine and Artificial Intelligence: The Perfect Fit for Autoimmunity covers background on artificial intelligence (AI), its link to precision medicine (PM), and examples of AI in healthcare, especially autoimmunity. The book highlights future perspectives and potential directions as AI has gained significant attention during the past decade. Autoimmune diseases are complex and heterogeneous conditions, but exciting new developments and implementation tactics surrounding automated systems have enabled the generation of large datasets, making autoimmunity an ideal target for AI and…mehr
Precision Medicine and Artificial Intelligence: The Perfect Fit for Autoimmunity covers background on artificial intelligence (AI), its link to precision medicine (PM), and examples of AI in healthcare, especially autoimmunity. The book highlights future perspectives and potential directions as AI has gained significant attention during the past decade. Autoimmune diseases are complex and heterogeneous conditions, but exciting new developments and implementation tactics surrounding automated systems have enabled the generation of large datasets, making autoimmunity an ideal target for AI and precision medicine. More and more diagnostic products utilize AI, which is also starting to be supported by regulatory agencies such as the Food and Drug Administration (FDA). Knowledge generation by leveraging large datasets including demographic, environmental, clinical and biomarker data has the potential to not only impact the diagnosis of patients, but also disease prediction, prognosis and treatment options. - Allows the readers to gain an overview on precision medicine for autoimmune diseases leveraging AI solutions - Provides background, milestone and examples of precision medicine - Outlines the paradigm shift towards precision medicine driven by value-based systems - Discusses future applications of precision medicine research using AI - Other aspects covered in the book include regulatory insights, data analytics and visualization, types of biomarkers as well as the role of the patient in precision medicine
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Inhaltsangabe
1. History, current status, and future directions of artificial intelligence Olga Kubassova, Faiq Shaikh, Carlos Melus, and Michael Mahler 2. Precision medicine as an approach to autoimmune diseases Marvin J. Fritzler and Michael Mahler 3. Biomarker and data science as integral part of precision medicine Carlos Melus, Brenden Rossin, Mary Ann Aure, and Michael Mahler 4. Companion and complementary diagnostics: A key to precision medicine Jan Trøst Jørgensen 5. Checkpoint inhibitors: Interface of cancer and autoimmunity: Opportunity for second level precision medicine Savino Sciascia, Marie Hudson, Marvin J. Fritzler, Minoru Satoh, and Michael Mahler 6. The evolving potential of precision medicine in the management of autoimmune liver disease Gary L. Norman, Nicola Bizzaro, Danilo Villalta, Diego Vergani, Giorgina Mieli-Vergani, Gideon M. Hirschfield, and Michael Mahler 7. Precision medicine in autoimmune disease Kevin D. Deane 8. Development of multi-omics approach in autoimmune diseases May Y. Choi, Marvin J. Fritzler, and Michael Mahler 9. N-of-1 trials: Implications for clinical practice and personalized clinical trials Joanne Bradbury and Michael Mahler 10. Health risk assessment and family history: Toward disease prevention Lily W. Martin, Lauren C. Prisco, Laura Martinez-Prat, Michael Mahler, and Jeffrey A. Sparks 11. Regulatory aspects of artificial intelligence and machine learning-enabled software as medical devices (SaMD) Michael Mahler, Carolina Auza, Roger Albesa, Carlos Melus, and Jungen Andrew Wu 12. Precision medicine from the patient's perspective: More opportunities and increasing responsibilities Kim MacMartin-Moglia and Michael Mahler
1. History, current status, and future directions of artificial intelligence Olga Kubassova, Faiq Shaikh, Carlos Melus, and Michael Mahler 2. Precision medicine as an approach to autoimmune diseases Marvin J. Fritzler and Michael Mahler 3. Biomarker and data science as integral part of precision medicine Carlos Melus, Brenden Rossin, Mary Ann Aure, and Michael Mahler 4. Companion and complementary diagnostics: A key to precision medicine Jan Trøst Jørgensen 5. Checkpoint inhibitors: Interface of cancer and autoimmunity: Opportunity for second level precision medicine Savino Sciascia, Marie Hudson, Marvin J. Fritzler, Minoru Satoh, and Michael Mahler 6. The evolving potential of precision medicine in the management of autoimmune liver disease Gary L. Norman, Nicola Bizzaro, Danilo Villalta, Diego Vergani, Giorgina Mieli-Vergani, Gideon M. Hirschfield, and Michael Mahler 7. Precision medicine in autoimmune disease Kevin D. Deane 8. Development of multi-omics approach in autoimmune diseases May Y. Choi, Marvin J. Fritzler, and Michael Mahler 9. N-of-1 trials: Implications for clinical practice and personalized clinical trials Joanne Bradbury and Michael Mahler 10. Health risk assessment and family history: Toward disease prevention Lily W. Martin, Lauren C. Prisco, Laura Martinez-Prat, Michael Mahler, and Jeffrey A. Sparks 11. Regulatory aspects of artificial intelligence and machine learning-enabled software as medical devices (SaMD) Michael Mahler, Carolina Auza, Roger Albesa, Carlos Melus, and Jungen Andrew Wu 12. Precision medicine from the patient's perspective: More opportunities and increasing responsibilities Kim MacMartin-Moglia and Michael Mahler
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