Precision Molecular Pathology of Liver Cancer (eBook, PDF)

Redaktion: Liu, Chen

• Format: PDF

Produktbeschreibung

Provides the most updated knowledge on hepatocellular carcinoma

Features instructive illustrations and tables

Written by experts in the field

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Produktdetails

• Verlag: Springer International Publishing
• Seitenzahl: 271
• Erscheinungstermin: 9. Januar 2018
• Englisch
• ISBN-13: 9783319680828
• Artikelnr.: 52938695

Autorenporträt

Chen Liu, MD University of Florida FL, USA

Inhaltsangabe

Overview: Current diagnosis and treatment of HCC in the era of precision medicine.- The etiology and pathogenesis of hepatocellular carcinoma.- Histological classification of HCC and its clinical implication.- Molecular classification of HCC and precision medicine.- Recent advances in HCC genomics, next generation sequencing, and bioinformatics.- Epigenetic regulations in the pathogenesis of HCC and the clinical application.- Biomarker discovery and validation in HCC diagnosis, prognosis, and therapy.- HCC cancer stem cell signaling pathway.- Epithelial and mesenchymal transition (EMT) and its biological significance in HCC.- HCC metastasis and circulating tumor cells.- Biological role and potential clinical application of miRNA in hepatocellular carcinoma.- Immune regulation in HCC and the prospect of immunotherapy.- Liver cell dysplasia and the development of HCC.- Molecular pathogenesis of hepatic adenoma and its malignant transformation.- The role of liver biopsy in HCC early diagnosis and treatment decision.- The future prospect on surgical approaches for HCC.- The future prospect on targeted therapy for HCC.