Protein Interactions (eBook, ePUB)

The Molecular Basis of Interactomics
Redaktion: Helms, Volkhard; Kalinina, Olga V.

• Format: ePub

Produktbeschreibung

This keenly awaited resource for the new field of interactomics systematically covers all types of cellular interactions that proteins engage in, including interactions with other proteins, DNA, RNA, membranes and small molecules.

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Produktdetails

• Verlag: Wiley-VCH
• Erscheinungstermin: 8. November 2022
• Englisch
• ISBN-13: 9783527830527
• Artikelnr.: 66400524

Autorenporträt

Volkhard Helms is Professor for Bioinformatics at Saarland University, Germany. He holds a Ph.D. from EMBL Heidelberg and has authored over 200 scientific publications. In 2000 he was named an EMBO Young Investigator. Olga Kalinina is Professor for Drug Bioinformatics at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)/Helmholtz Centre for Infection Research (HZI) and Saarland University, Germany. She holds a Ph.D. from the Engelhardt Institute for Molecular Biology of the Russian Academy of Sciences, and has authored over 50 scientific publications.

Inhaltsangabe

Protein Structure and Conformational Dynamics
Protein-Protein Binding Interfaces
Correlated Co-evolving Mutations at Protein-Protein Interfaces
Protein-Protein-Docking
Identification of Putative Protein Complexes in Protein-Protein Interaction Networks
Structures, Composition, and Modelling of Protein Complexes
Live-Cell Structural Biology to Solve Molecular Mechanisms: Structural Dynamics in the Exocyst Function
Kinetics and Thermodynamics of Protein-Protein Encounter
Markov-State Models for Protein-Protein Encounter
Transcription Factor-DNA Complexes
Chromatin Interactomics
Interactions of Proteins with mRNA and ncRNA
Interactions Between Proteins and Biological Membranes
Interactions of Proteins with Small Molecules
Effects of Mutations in Proteins on Their Interactions
Not Quite the Same: How Alternative Splicing Affects Protein Interactions
Phosphorylation-based Molecular Switches
Summary and Outlook