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This keenly awaited resource for the new field of interactomics systematically covers all types of cellular interactions that proteins engage in, including interactions with other proteins, DNA, RNA, membranes and small molecules.
This keenly awaited resource for the new field of interactomics systematically covers all types of cellular interactions that proteins engage in, including interactions with other proteins, DNA, RNA, membranes and small molecules.
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Autorenporträt
Volkhard Helms is Professor for Bioinformatics at Saarland University, Germany. He holds a Ph.D. from EMBL Heidelberg and has authored over 200 scientific publications. In 2000 he was named an EMBO Young Investigator. Olga Kalinina is Professor for Drug Bioinformatics at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)/Helmholtz Centre for Infection Research (HZI) and Saarland University, Germany. She holds a Ph.D. from the Engelhardt Institute for Molecular Biology of the Russian Academy of Sciences, and has authored over 50 scientific publications.
Inhaltsangabe
Protein Structure and Conformational Dynamics Protein-Protein Binding Interfaces Correlated Co-evolving Mutations at Protein-Protein Interfaces Protein-Protein-Docking Identification of Putative Protein Complexes in Protein-Protein Interaction Networks Structures, Composition, and Modelling of Protein Complexes Live-Cell Structural Biology to Solve Molecular Mechanisms: Structural Dynamics in the Exocyst Function Kinetics and Thermodynamics of Protein-Protein Encounter Markov-State Models for Protein-Protein Encounter Transcription Factor-DNA Complexes Chromatin Interactomics Interactions of Proteins with mRNA and ncRNA Interactions Between Proteins and Biological Membranes Interactions of Proteins with Small Molecules Effects of Mutations in Proteins on Their Interactions Not Quite the Same: How Alternative Splicing Affects Protein Interactions Phosphorylation-based Molecular Switches Summary and Outlook
Protein Structure and Conformational Dynamics Protein-Protein Binding Interfaces Correlated Co-evolving Mutations at Protein-Protein Interfaces Protein-Protein-Docking Identification of Putative Protein Complexes in Protein-Protein Interaction Networks Structures, Composition, and Modelling of Protein Complexes Live-Cell Structural Biology to Solve Molecular Mechanisms: Structural Dynamics in the Exocyst Function Kinetics and Thermodynamics of Protein-Protein Encounter Markov-State Models for Protein-Protein Encounter Transcription Factor-DNA Complexes Chromatin Interactomics Interactions of Proteins with mRNA and ncRNA Interactions Between Proteins and Biological Membranes Interactions of Proteins with Small Molecules Effects of Mutations in Proteins on Their Interactions Not Quite the Same: How Alternative Splicing Affects Protein Interactions Phosphorylation-based Molecular Switches Summary and Outlook
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