Protein-Protein Interactions in Human Disease, Part A (eBook, ePUB)

• Format: ePub

Produktbeschreibung

Protein-Protein Interactions in Human Disease, Part A, Volume 110 aims to promote further research and development in the protein interaction network as a means to not only identify the critical proteins involved in the etiology of human diseases, but also identify new protein targets for drug development. Sections cover such topics as protein-protein interaction modulators for epigenetic therapies, intrinsic disorder, protein-protein interactions and disease, targeting protein-protein interactions in the ubiquitin-proteasome pathway, the proteomics of occupational diseases, and computational methods in predicting the impact of SNPs in protein-protein network, amongst other topics.

• Describes advances in the application of powerful techniques in studying and analyzing protein-protein interactions
• Targeted to a wide audience of researchers, specialists and students
• Written by authorities in their field
• Includes information that is well supported by a number of high quality illustrations, figures and tables

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 288
• Erscheinungstermin: 3. Februar 2018
• Englisch
• ISBN-13: 9780128143452
• Artikelnr.: 55359250

Inhaltsangabe

1. Analysis of protein interactions by surface plasmon resonance
Dennis G. Drescher
2. Using TR-FRET to investigate protein-protein interactions: a case study of PXR-coregulator interaction
Taosheng Chen
3. Protein-Protein Interaction Modulators for Epigenetic Therapies
Jose L. Medina-Franco
4. Intrinsic disorder, protein-protein interactions and disease
Vladimir N. Uversky
5. Targeting protein-protein interactions in the ubiquitin-proteasome pathway
Maria Gaczynska
6. Protein-protein networks involved in MODY family
George Priya Doss P. C
7. Defining HIV-1 replication mechanisms by analyzing virus-host protein interactions
Manuel Llano
8. Proteomics of occupational diseases
Nicola Luigi Bragazzi
9. Proteomics of sport-related injuries
Nicola Luigi Bragazzi
10. Structural prediction of protein-protein interactions by docking: application to biomedical problems
Juan Fernandez-Recio
11. Computational methods in predicting the impact of SNPs in Protein-protein network
George Priya Doss P. C

Rezensionen

"...all of the authors of the book succeeded in showing highly exciting and unique opportunities for unraveling the functional behavior of complex protein-protein interactions in human diseases. ...The volume shows the enormous complexity in the field of PPI in human diseases. It is a collection of topics without pretending in-depth analysis of a single subject. Each theme and chapter stands on its own, but all have protein-protein interactions in common." --The Quarterly Review of Biology