Regulation of Signal Transduction in Human Cell Research (eBook, PDF)

Redaktion: Shinomiya, Nariyoshi; Xie, Qian; Kataoka, Hiroaki

• Format: PDF

Produktbeschreibung

Focuses on the relationship between the regulation of signal transduction and disease mechanisms Highlights essential molecules and intracellular signaling pathways Help readers understand how the dysregulation of intracellular signals leads to diseases

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Produktdetails

• Verlag: Springer Nature Singapore
• Seitenzahl: 218
• Erscheinungstermin: 15. Februar 2018
• Englisch
• ISBN-13: 9789811072963
• Artikelnr.: 52944680

Autorenporträt

Editors: Nariyoshi Shinomiya Department of Integrative Physiology and BiöNano Medicine, National Defense Medical College, Tokorozawa, Japan Hiroaki Kataoka Department of Pathology, University of Miyazaki, Miyazaki, Japan Qian Xie Department of Biomedical Sciences, East Tennessee State University, Johnson City, TN, USA

Inhaltsangabe

1. Regulation of microRNA expression by growth factors.- 2. TGF-b signaling and epithelial mesenchymal transition.- 3. Molecular designing of small molecule inhibitor for apoptotic pathways.- 4. Using genetically engineered mouse models to study Wnt signaling in bone development and disease.- 5. Glucose signaling and glycolysis.- 6. The interplay of tumor suppressor p53 with hypoxia-inducible factor-1 (HIF-1) at the crossroad between hypoxia-mediated cell survival and death.- 7. Role of G protein-coupled receptor signaling on the proliferation and differentiation of multipotent stem cells.- 8. Met-KO and carcinogenesis
9. Clinical impact of MET pathway in cancer.- 10. Pericellular proteolytic activation of growth factors.