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Science of Synthesis: Houben-Weyl Methods of Molecular Transformations is the entirely new edition of the acclaimed reference series Houben-Weyl, the standard synthetic chemistry resource since 1909. This new edition is published in English and will comprise 48 volumes published between the years 2000 and 2008. Science of Synthesis is a quality reference work developed by a highly esteemed editorial board to provide a comprehensive and critical selection of reliable organic and organometallic synthetic methods. This unique resource is designed to be the first point of reference when…mehr
Science of Synthesis: Houben-Weyl Methods of Molecular Transformations is the entirely new edition of the acclaimed reference series Houben-Weyl, the standard synthetic chemistry resource since 1909. This new edition is published in English and will comprise 48 volumes published between the years 2000 and 2008.
Science of Synthesis is a quality reference work developed by a highly esteemed editorial board to provide a comprehensive and critical selection of reliable organic and organometallic synthetic methods. This unique resource is designed to be the first point of reference when searching for a synthesis strategy.
Contains the expertise of presently 400 leading chemists worldwide
Critically evaluates the preparative applicability and significance of the synthetic methods
Discusses relevant background information and provides detailed experimental procedures
For full information on the Science of Synthesis series, visit the Science of Synthesis Homepage
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Autorenporträt
Houben-Weyl
Inhaltsangabe
35.1 Product Class 1: One Saturated Carbon—Chlorine Bond 35.1.1 Product Subclass 1: Chloroalkanes 35.1.1.1 Synthesis by Substitution of Hydrogen 35.1.1.2 Synthesis by Substitution of Metals 35.1.1.3 Synthesis by Substitution of Carbon Functionalities 35.1.1.4 Synthesis by Substitution of Other Halogens 35.1.1.5 Synthesis by Substitution of Oxygen Functionalities 35.1.1.6 Synthesis by Substitution of Sulfur, Selenium, or Tellurium Functionalities 35.1.1.7 Synthesis by Substitution of Nitrogen Functionalities 35.1.1.8 Synthesis by Addition to π-Type C—C Bonds 35.1.1.9 Synthesis from Other Chlorine Compounds 35.1.2 Product Subclass 2: Propargylic Chlorides 35.1.3 Product Subclass 3: Benzylic Chlorides 35.1.3.1 Synthesis by Substitution of Hydrogen 35.1.3.2 Synthesis by Substitution of Carbonyl Oxygen 35.1.3.3 Synthesis by Substitution of σ-Bonded Heteroatoms 35.1.4 Product Subclass 4: Allylic Chlorides 35.1.4.1 Synthesis by Substitution of Hydrogen α to a C=C Bond 35.1.4.2 Synthesis by Substitution of σ-Bonded Heteroatoms 35.1.5 Product Subclass 5: 1-Chloro-n-Heteroatom-Functionalized Alkanes (n ≥2) with Both Functions Formed Simultaneously 35.1.5.1 Synthesis by Addition across C=C Bonds 35.1.5.2 Synthesis by Addition across C—O Bonds 35.1.5.3 Synthesis by Addition across C—S Bonds 35.1.5.4 Synthesis by Addition across C—N Bonds 35.1.5.5 Synthesis by Addition across C—C Bonds 35.2 Product Class 2: One Saturated Carbon—Bromine Bond 35.2.1 Product Subclass 1: Bromoalkanes 35.2.1.1 Synthesis by Substitution of Hydrogen 35.2.1.2 Synthesis by Substitution of Metals 35.2.1.3 Substitution of Carbon Functionalities 35.2.1.4 Synthesis by Substitution of Other Halogens 35.2.1.5 Synthesis by Substitution of Oxygen Functionalities 35.2.1.6 Synthesis by Substitution of Sulfur, Selenium, or Tellurium Functionalities 35.2.1.7 Synthesis by Substitution of Nitrogen Functionalities 35.2.1.8 Synthesis by Addition to π-Type C—C Bonds 35.2.1.9 Synthesis from Other Bromo Compounds 35.2.2 Product Subclass 2: Propargylic Bromides 35.2.3 Product Subclass 3: Benzylic Bromides 35.2.3.1 Synthesis by Substitution of Hydrogen 35.2.3.2 Synthesis by Substitution of Carbonyl Oxygen 35.2.3.3 Synthesis by Substitution of σ-Bonded Heteroatoms 35.2.4 Product Subclass 4: Allylic Bromides 35.2.4.1 Synthesis by Substitution of Hydrogen α to a C=C Bond 35.2.4.2 Synthesis by Substitution of σ-Bonded Heteroatoms 35.2.5 Product Subclass 5: 1-Bromo-n-Heteroatom-Functionalized Alkanes (n ≥2) with Both Functions Formed Simultaneously 35.2.5.1 Synthesis by Addition across C=C Bonds 35.2.5.2 Synthesis by Addition across C—O Bonds 35.2.5.3 Synthesis by Addition across C—S Bonds 35.2.5.4 Synthesis by Addition across C—N Bonds 35.2.5.5 Synthesis by Addition across C—C Bonds 35.3 Product Class 3: One Saturated Carbon—Iodine Bond 35.3.1 Product Subclass 1: Iodoalkanes 35.3.1.1 Synthesis by Substitution of Hydrogen 35.3.1.2 Synthesis by Substitution of Metals 35.3.1.3 Synthesis by Substitution of Carbon Functionalities 35.3.1.4 Synthesis by Substitution of Other Halogens 35.3.1.5 Synthesis by Substitution of Oxygen Functionalities 35.3.1.6 Synthesis by Substitution of Sulfur, Selenium, or Tellurium Functionalities 35.3.1.7 Synthesis by Substitution of Nitrogen Functionalities 35.3.1.8 Synthesis by Addition to π-Type C—C Bonds 35.3.1.9 Synthesis from Other Iodo Compounds 35.3.2 Product Subclass 2: Propargylic Iodides 35.3.3 Product Subclass 3: Benzylic Iodides 35.3.3.1 Synthesis by Substitution of Carbonyl Oxygen 35.3.3.2 Substitution of σ-Bonded Heteroatoms 35.3.4 Product Subclass 4: Allylic Iodides 35.3.5 Product Subclass 5: 1-Iodo-n-Heteroatom-Functionalized Alkanes (n ≥2) with Both Functions Formed Simultaneously 35.3.5.1 Synthesis by Addition across C=C Bonds 35.3.5.2 Synthesis by Addition across C—O Bonds 35.3.5.3 Synthesis by Addition across C—S Bonds 35.3.5.4 Synthesis by Addition across C—N Bonds 35.3.5.5 Synthesis by Addition across C—C Bonds
35.1 Product Class 1: One Saturated Carbon—Chlorine Bond 35.1.1 Product Subclass 1: Chloroalkanes 35.1.1.1 Synthesis by Substitution of Hydrogen 35.1.1.2 Synthesis by Substitution of Metals 35.1.1.3 Synthesis by Substitution of Carbon Functionalities 35.1.1.4 Synthesis by Substitution of Other Halogens 35.1.1.5 Synthesis by Substitution of Oxygen Functionalities 35.1.1.6 Synthesis by Substitution of Sulfur, Selenium, or Tellurium Functionalities 35.1.1.7 Synthesis by Substitution of Nitrogen Functionalities 35.1.1.8 Synthesis by Addition to π-Type C—C Bonds 35.1.1.9 Synthesis from Other Chlorine Compounds 35.1.2 Product Subclass 2: Propargylic Chlorides 35.1.3 Product Subclass 3: Benzylic Chlorides 35.1.3.1 Synthesis by Substitution of Hydrogen 35.1.3.2 Synthesis by Substitution of Carbonyl Oxygen 35.1.3.3 Synthesis by Substitution of σ-Bonded Heteroatoms 35.1.4 Product Subclass 4: Allylic Chlorides 35.1.4.1 Synthesis by Substitution of Hydrogen α to a C=C Bond 35.1.4.2 Synthesis by Substitution of σ-Bonded Heteroatoms 35.1.5 Product Subclass 5: 1-Chloro-n-Heteroatom-Functionalized Alkanes (n ≥2) with Both Functions Formed Simultaneously 35.1.5.1 Synthesis by Addition across C=C Bonds 35.1.5.2 Synthesis by Addition across C—O Bonds 35.1.5.3 Synthesis by Addition across C—S Bonds 35.1.5.4 Synthesis by Addition across C—N Bonds 35.1.5.5 Synthesis by Addition across C—C Bonds 35.2 Product Class 2: One Saturated Carbon—Bromine Bond 35.2.1 Product Subclass 1: Bromoalkanes 35.2.1.1 Synthesis by Substitution of Hydrogen 35.2.1.2 Synthesis by Substitution of Metals 35.2.1.3 Substitution of Carbon Functionalities 35.2.1.4 Synthesis by Substitution of Other Halogens 35.2.1.5 Synthesis by Substitution of Oxygen Functionalities 35.2.1.6 Synthesis by Substitution of Sulfur, Selenium, or Tellurium Functionalities 35.2.1.7 Synthesis by Substitution of Nitrogen Functionalities 35.2.1.8 Synthesis by Addition to π-Type C—C Bonds 35.2.1.9 Synthesis from Other Bromo Compounds 35.2.2 Product Subclass 2: Propargylic Bromides 35.2.3 Product Subclass 3: Benzylic Bromides 35.2.3.1 Synthesis by Substitution of Hydrogen 35.2.3.2 Synthesis by Substitution of Carbonyl Oxygen 35.2.3.3 Synthesis by Substitution of σ-Bonded Heteroatoms 35.2.4 Product Subclass 4: Allylic Bromides 35.2.4.1 Synthesis by Substitution of Hydrogen α to a C=C Bond 35.2.4.2 Synthesis by Substitution of σ-Bonded Heteroatoms 35.2.5 Product Subclass 5: 1-Bromo-n-Heteroatom-Functionalized Alkanes (n ≥2) with Both Functions Formed Simultaneously 35.2.5.1 Synthesis by Addition across C=C Bonds 35.2.5.2 Synthesis by Addition across C—O Bonds 35.2.5.3 Synthesis by Addition across C—S Bonds 35.2.5.4 Synthesis by Addition across C—N Bonds 35.2.5.5 Synthesis by Addition across C—C Bonds 35.3 Product Class 3: One Saturated Carbon—Iodine Bond 35.3.1 Product Subclass 1: Iodoalkanes 35.3.1.1 Synthesis by Substitution of Hydrogen 35.3.1.2 Synthesis by Substitution of Metals 35.3.1.3 Synthesis by Substitution of Carbon Functionalities 35.3.1.4 Synthesis by Substitution of Other Halogens 35.3.1.5 Synthesis by Substitution of Oxygen Functionalities 35.3.1.6 Synthesis by Substitution of Sulfur, Selenium, or Tellurium Functionalities 35.3.1.7 Synthesis by Substitution of Nitrogen Functionalities 35.3.1.8 Synthesis by Addition to π-Type C—C Bonds 35.3.1.9 Synthesis from Other Iodo Compounds 35.3.2 Product Subclass 2: Propargylic Iodides 35.3.3 Product Subclass 3: Benzylic Iodides 35.3.3.1 Synthesis by Substitution of Carbonyl Oxygen 35.3.3.2 Substitution of σ-Bonded Heteroatoms 35.3.4 Product Subclass 4: Allylic Iodides 35.3.5 Product Subclass 5: 1-Iodo-n-Heteroatom-Functionalized Alkanes (n ≥2) with Both Functions Formed Simultaneously 35.3.5.1 Synthesis by Addition across C=C Bonds 35.3.5.2 Synthesis by Addition across C—O Bonds 35.3.5.3 Synthesis by Addition across C—S Bonds 35.3.5.4 Synthesis by Addition across C—N Bonds 35.3.5.5 Synthesis by Addition across C—C Bonds
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