Stem Cell Genetics for Biomedical Research (eBook, PDF)

Past, Present, and Future
Redaktion: Delgado-Morales, Raul

• Format: PDF

Produktbeschreibung

This volume presents an up-to-date compendium of major scientific breakthroughs on human diseases, drug screenings, personalized medicine and regenerative approaches by using stem cells to model or treat the disorders

This book covers what would be the desired strategy for the years to come, by methodically dissecting limitations in our current methodology and understanding of stem cells technology

This book also summarizes state-of-the-art technology (genomics and epigenomics, crispr/cas9, epigenetic tools, bioinformatics approaches, etc) that will push further the applicability and validity of the stem cell application in biomedical research

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Produktdetails

• Verlag: Springer International Publishing
• Seitenzahl: 426
• Erscheinungstermin: 27. Juni 2018
• Englisch
• ISBN-13: 9783319906959
• Artikelnr.: 53071780

Autorenporträt

Raul Delgado-Morales holds a PhD in Neuroscience. He completed his doctoral studies at the Universitat Autònoma de Barcelona working in the field of epigenetics as it relates to depression. After that he received a Marie Curie Postdoctoral Fellowship, to continue his research as a postdoc at the Max Planck Institute of Psychiatry in Munich. There he focused on Alzheimer's disease. After four years in Germany, he moved to Bellvitge Biomedical Research Institute (IDIBELL), in Barcelona, to lead research on neuroepigenomics. Currently he is the Scientific Deputy Director of IDIBELL.

Inhaltsangabe

Part I: Stem cells for brain disorders.- Chapter1: Human induced pluripotent stem cell-derived neurons to model and gain insights into Alzheimer's disease pathogenesis.- Chapter2: Modeling schizophrenia with human stem cells.- Chapter3: Rett Syndrome and Stem Cell research.- Chapter4: Stem Cell Applications in Spinal Cord Injury: A Primer.- Chapter5: Cell-Based Therapy for Retinal Degenerative Disease.- Chapter6: Past, present and future of cell based-therapy in progressive multiple sclerosis.- Part II: Stem cells for cardiovascular diseases.- Chapter7: Cardiac Stem Cells: a plethora of potential therapies for myocardial regeneration within reach.- Chapter8: Human Induced Pluripotent Stem Cell-derived Cardiomyocytes in the Evaluation of Cardiotoxic Potential of Drugs.- Part III: Stem cells for general medicine.- Chapter9: Regenerative medicine for diabetes treatment: new beta-cell sources.- Chapter10: Dental pulp stem cells promote wound healing and muscle regeneration.- Chapter11: From bench to bedside of mesenchymal Stem Cells use for Rheumatoid Arthritis treatment.- Chapter12: Stem Cells and Cancer.- Chapter13: The relevance of induced pluripotent stem cells for the study of physiological and premature aging.- Part IV: Technical challenges and future.- Chapter14: Pluripotent stem cell banks.- Chapter15: Genetic and Epigenetic engineering: the CRISPR/Cas9 era.