Kenneth Kee

Sweet's Syndrome, A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions (eBook, ePUB)

• Format: ePub

Produktbeschreibung

This book describes Sweet's Syndrome, Diagnosis and Treatment and Related Diseases
Sweet's Syndrome is a rare, benign skin disorder, with a sudden start of fever and painful red, inflamed skin lesions that are infiltrated by neutrophils (a type of white blood cell)
These lesions normally happen on the arms, legs, trunk, face or neck.
More systems of the body can become affected such as:
1. The musculoskeletal system such as inflammation of the joints (arthritis),
2. The eyes such as inflammation of the conjunctiva or the membrane that lines the eyes (conjunctivitis), and
3. The internal organs.
There are 3 main groups of Sweet's Syndrome:

1. Idiopathic Sweet's Syndrome:
The syndrome is normally present in adults between the ages 30-60 years
Women are more likely to develop the disorder than men (in a 4:1 ratio)
Idiopathic Sweet's Syndrome recurs in one-third of the patients
In the majority of involved patients, the disorder happens by itself for no known reason (idiopathic Sweet's Syndrome)
2. Malignancy-Linked Sweet's Syndrome:
The skin findings may indicate cancer repeat occurrence or an undiagnosed cancer
Less often, the disorder can be linked with an underlying cancer (malignancy), normally a blood (hematological) cancer such as leukemia
3. Drug-Induced Sweet's Syndrome:
Persons, who are exposed to certain drugs, may develop the syndrome
The disorder can also happen as a reaction to taking certain medicines, mostly a drug known as granulocyte-colony stimulating factor

Causes
The cause of Idiopathic Sweet's Syndrome and Malignancy-Associated Sweet's Syndrome is not known
The drugs linked with Drug-Induced Sweet's Syndrome are:
1. Granulocyte colony-stimulating factor (G-CSF)
2. Bortezomib
3. Azacitidine
4. Decitabine
5. Imatinib mesylate
Other times, it happens when the immune system reacts to another disorder:
1. Blood cancer such as leukemia or lymphoma
2. Bowel disease, like ulcerative colitis or Crohn's disease
3. Chest infection or strep throat
4. Colon or breast cancer
5. Injury where the rash is, like a needle prick or insect bite

Symptoms
1. Fever (that may be high or moderate), tiredness, headache, aches in the joints, skin sores

a. Idiopathic Sweet's Syndrome is featured by the rapid onset of painful, red, inflamed skin lesions, infiltrated by neutrophils without inflammation of blood vessels
b. 75-90% of patients with Idiopathic Sweet's Syndrome and 20% of patients with Malignancy-Associated Sweet's Syndrome
report an upper respiratory infection before the manifestation of Sweet's Syndrome

Diagnosis
The doctor might be able to tell that it is Sweet's Syndrome just by looking at the rash.
Sweet's Syndrome is linked with these major criteria:
1. Rapid onset of painful skin lesions
2. Skin biopsy reveals histopathologic features of neutrophilic infiltration

Treatment

Sweet's syndrome may go away without treatment.
A treatment of Sweet's Syndrome may involve:
1. Sweet's Syndrome is often treated with 4-6 weeks of intravenous, oral or topical corticosteroids, dependent on the extensiveness of the skin findings.
2. The length of treatment is dependent on the disorder
3. Other medicines may be potassium iodide, colchicine, dapsone, and cyclosporine
4. In Malignancy-Linked Sweet's Syndrome, the treatment of the underlying malignancy may treat the disease
5. In Drug-Induced Sweet's Syndrome, stopping or temporary cessation of the causative drug may treat the disease
6. Antibiotics may be essential
Treatment of the underlying cancer results in the resolution of symptoms in malignancy-linked Sweet's Syndrome.
Drug-induced Sweet's Syndrome symptoms normally disappear after stopping causative drug

TABLE OF CONTENT
Introduction
Chapter 1 Sweet's Syndrome...

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Produktdetails

• Verlag: Kenneth Kee
• Erscheinungstermin: 9. August 2018
• Englisch
• ISBN-13: 9780463377819
• Artikelnr.: 53545798

Autorenporträt

Dr. Kenneth Kee is a well-known medical doctor from Singapore who has been practicing medicine since 1972.
He graduated from the University of Singapore and furthered his studies with a Master of Science in Health Management in 1991, followed by a Ph.D. in Healthcare Administration in 1993.
Dr. Kee established Kee Clinic in 1974, located in the Holland Drive area of Singapore. The clinic has been a prominent feature of the community, offering general medical services for 5 decades.
Dr Kee also served his country Singapore as a national service police Inspector at night from 1975 to 1985 while working at his clinic during the day.
He had served as a police guard to the Woodland Petroleum Tanks at night during the Indonesian Confrontation period, took part in police rounds at night in the Beach Road area and taught First aid and emergency resuscitation to Police recruits.
He received the Singapore Police Bicentennial 2020 Medallion on 1st March 2024 as recognition for his work in the Singapore Police.
Even as he grew older, Dr. Kee continued to work actively in his clinic, although he eventually reduced his consultation hours.
Beyond his medical career, Dr. Kee is also an author.
He started writing about medical conditions in 2007, using blogs and other online platforms to share his knowledge with a broader audience.
Over time, he published various books, many of which provide simple and accessible guides to different health conditions.
His works include "A Family Doctor's Tale," "My Personal Singapore History," and numerous medical guides, available through platforms like Amazon.
His books often combine his personal experiences as a family doctor with insights into Singapore's healthcare system and history.
Dr. Kee has written extensively on health topics, contributing to both medical literature and general knowledge resources.

Dr. Kenneth Kee has written numerous books, primarily focused on health education and personal experiences as a family doctor. Some of his notable titles include:
"A Family Doctor's Tale"
This book is a blend of Dr. Kee's personal experiences and his reflections on being a family doctor in Singapore. It's a great choice if you're looking for a narrative that combines both medical knowledge and human stories.
"Specialized Medical Conditions"
Books like **"Congestive Heart Failure: Diagnosis and Treatment"** focus on specific conditions, offering in-dept...