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"This book is written for basic science and clinical researchers ... . Biomedical scientists involved in genomics/proteomics research and drug discovery will also appreciate the wealth of information and interesting new concepts presented. ... The chapters are well written and the topics are interesting. ... the book is intended both for advanced students and experts in theoretical systems biology. ... The authors illustrate their work nicely and provide general readers with a vision of future developments expected in cellular engineering." (Bruce A. Fenderson, Doody's Review Service, August, 2008)