Targeted Drug Delivery (eBook, PDF)

Redaktion: Bachhav, Yogeshwar

• Format: PDF

Produktbeschreibung

Highlights the critical role of targeted drug delivery for unmet medical needs, by describing a wide range of different approaches for targeting small molecule as well as peptide and macromolecular drugs.

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Produktdetails

• Verlag: Wiley-VCH
• Seitenzahl: 464
• Erscheinungstermin: 17. Oktober 2022
• Englisch
• ISBN-13: 9783527827862
• Artikelnr.: 66225329

Autorenporträt

Yogeshwar Bachhav is a pharmacist by training and holds a PhD in drug delivery systems from ICT, Mumbai (India). He has worked as research scientist for several years on a collaborative project between Pantec Biosolutions and Geneva University (Switzerland), and as formulation manager at Debiopharm Group, Lausanne (Switzerland). For the last 9 years he has been associated with AiCuris Anti-infective Cures AG (Germany) as in-charge for Pharmaceutical development of new drugs. In total, he has around 16 years of experience in the preformulation and formulation development of small molecules and peptides for oral, dermal and parenteral application and in drug substance manufacturing.

Inhaltsangabe

Basics of Targeted Drug Delivery
Addressing Unmet Medical Needs using Targeted Drug Delivery Systems: Emphasis on Nanomedicine-Based Applications
Nanocarriers Based Targeted Drug Delivery Systems: Small and Macromolecules
Liposomes as Targeted Drug Delivery Systems
Antibody-Drug Conjugates: Development and Applications
Gene-Directed Enzyme Prodrug Therapy (GDEPT) as a Suicide Gene Therapy Modality for Cancer Treatment
Targeted Prodrugs in Oral Drug Delivery
Exosomes for Drug Delivery Applications in Cancer and Cardiac Indications
Delivery of Nucleic Acids such as siRNA and mRNA using Complex Formulations
Application of PROTAC Technology in Drug Development
Metal Complexes as the Means or the End of Targeted Delivery for Unmet Needs
Formulation of Peptides for Targeted Delivery
Antibody-Based Targeted T Cell Therapies
Devices for Active Targeted Delivery: A Way to Control the Rate and Extent of Drug Administration
Drug Delivery to the Brain: Targeting Technologies to Delivery Therapeutics to Brain Lesions