Taxus (eBook, ePUB)

The Genus Taxus
Redaktion: Itokawa, Hideji; Lee, Kuo-Hsiung

• Format: ePub

Produktbeschreibung

Taxol, originally derived from the North American Yew tree in 1971, is well-known worldwide as a powerful anticancer agent. Mechanistically, it has a unique microtubule stabilizing activity, and was clinically developed as a therapeutic agent in the treatment of breast and ovarian cancers at the National Cancer Institute, Washington D.C., USA. I

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Produktdetails

• Verlag: Taylor & Francis eBooks
• Seitenzahl: 386
• Erscheinungstermin: 13. Februar 2003
• Englisch
• ISBN-13: 9781134427666
• Artikelnr.: 59892992

Autorenporträt

Hideji Itokawa, Kuo-Hsiung Lee

Inhaltsangabe

1. Introduction 2. Biosynthesis of Taxoids 3. Taxoids Occurring in the
genus Taxus 4. Physical Methods for Identifying the Structures of Taxoids
5. Plant Tissue Culture of Taxoids 6. The Commercial Cultivation of Taxus
Species and Production of Taxoids 7. Analytical Aspects of Taxoids 8.
Chemistry of Taxol and Related Taxoids 9. Total Synthesis of Taxoids 10.
Structure-Activity Relationships of Taxoids 11. Pre-clinical and Clinical
Investigation of the Taxanes 12. Paclitaxel Content of Yews in Ireland