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Scientific Study from the year 2025 in the subject Biology - Diseases, Health, Nutrition, , language: English, abstract: Obesity and Type 2 Diabetes Mellitus (T2DM) are two of the most pressing public health challenges of the 21st century. While their association is well-documented, establishing a causal relationship is vital for guiding effective prevention strategies. This paper applies Bradford Hill's criteria for causation to systematically assess whether obesity can be considered a direct cause of T2DM. Drawing on evidence from epidemiological studies, clinical trials, and biological…mehr

Produktbeschreibung
Scientific Study from the year 2025 in the subject Biology - Diseases, Health, Nutrition, , language: English, abstract: Obesity and Type 2 Diabetes Mellitus (T2DM) are two of the most pressing public health challenges of the 21st century. While their association is well-documented, establishing a causal relationship is vital for guiding effective prevention strategies. This paper applies Bradford Hill's criteria for causation to systematically assess whether obesity can be considered a direct cause of T2DM. Drawing on evidence from epidemiological studies, clinical trials, and biological mechanisms, the paper evaluates the strength, consistency, temporality, dose-response, plausibility, and experimental support for the link. Findings reveal that obesity satisfies nearly all of Hill's nine criteria, including strong and consistent associations across populations, well-established temporal precedence, and mechanistic plausibility supported by experimental evidence. The paper concludes that the causal role of obesity in the development of T2DM is robust and should inform policy, clinical interventions, and public health strategies globally.

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Autorenporträt
Biography of Kingsley Adimabua: Kingsley Adimabua is a dedicated and experienced Humanitarian and Development worker hailing from Abuja, Nigeria. With a career spanning 11 years, Kingsley has made significant contributions to various esteemed organizations within the field. His passion for making a positive impact on communities and his expertise in Monitoring and Evaluation (M&E) and Information and Knowledge Management have set him apart as a strong candidate. Throughout his professional journey, Kingsley has had the privilege of working with reputable organizations such as Malaria Consortium, Christian Aid, Cuso International, Save the Children, Oxfam Novib, eHealth Africa, CBM International, and Palladium in Nigeria. His notable achievements include establishing a harmonized Post Distribution Monitoring system for a consortium of organizations involved in the Nigerian Joint Humanitarian Response and implementing effective Information and Knowledge management systems for Oxfam Novib's humanitarian response. Kingsley's skill set extends beyond M&E and Information and Knowledge Management. He possesses expertise in establishing quality standards and internal quality assurance mechanisms and is proficient in statistical analysis using tools such as Excel, STATA, SPSS, Epi-Info, and MicroStrategy. Additionally, his excellent writing and presentation skills have been honed through his professional experience. Passionate about helping people and driven by a desire to make a difference, Kingsley is a valuable asset to any team. He thrives on challenges, demonstrates adaptability, and possesses strong leadership qualities. Kingsley's unwavering dedication to humanitarian and development work, combined with his affinity for working with numbers and figures, make him a valuable addition to any organization. In his pursuit of professional growth, Kingsley is eager to take on increased responsibilities and contribute to an organization's growth in a higher role. He is patient, adaptable, and committed to exceeding expectations. Kingsley's ultimate goal is to continue making a positive impact on communities and contribute to the growth and success of the organization he joins. If given the opportunity, Kingsley would be delighted to discuss his qualifications further in an interview. For any inquiries or to schedule an interview, please feel free to contact him via email at greygoblings@gmail.com.