The Complement System (eBook, PDF)

Redaktion: Rother, K.; Hänsch, Gertrud M.; Till, Gerd O.

• Format: PDF

Produktbeschreibung

This is a comprehensive presentation of all aspects of the complement system, which plays a key role in immunological reactions. The second edition has been thoroughly revised, with additional chapters. It offers the present state of the art, compiled by leading experts in the field. Extensive literature citations offer easy access for those interested in more detail.

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Produktdetails

• Verlag: Springer Berlin Heidelberg
• Seitenzahl: 564
• Erscheinungstermin: 6. Dezember 2012
• Englisch
• ISBN-13: 9783642587535
• Artikelnr.: 53381183

Inhaltsangabe

1 Components and Reactivity.- 1.1 Components.- 1.2 Reactivity.- 1.3 Surface Receptors and Signaling Pathways.- 2 Biologic Functions.- 2.1 Complement in the Induction of Antibody Response.- 2.2 Maintenance of Immune Complex Solubility and Immune Adherence.- 2.3 Interaction with Effector Cells.- 2.4 Host Defense Against Infection.- 2.5 Possible Role of Complement Regulators in Reproduction.- 2.6 Network Interactions of the Complement System with Other Serum Mediator Systems.- 3 Pathology.- 3.1 Complement Deficiencies in Animals: Impact on Biological Functions.- 3.2 Complement Deficiencies in Humans.- 3.3 C3 Nephritic Factor.- 3.4 Complement in Inflammation.- 3.5 Role of Complement in Graft Rejection.- 3.6 Complement Activation on Artificial Surfaces in Biomedical Therapies.- 3.7 Adverse Reactions to Drugs.- 4 Complement Manipulation In Vivo.- 5 The Clinical Laboratory: Testing the Complement System.

Rezensionen

From the reviews of the first edition:
"Overall, the volume is a most useful resource on complement and will be of tremendous value for investigators in the area of complementology, newcomers in the field, and instructors for updating their information on the subject." ASM News - American Society for Microbiology