The Glutamate Receptors (eBook, PDF)

Redaktion: Gereau, Robert W.; Swanson, Geoffrey

• Format: PDF

Produktbeschreibung

Glutamate receptors are critically important for normal brain function. The last decade has seen remarkable advances in our understanding of the physiological function and molecular structure of these proteins. This book provides a detailed review of the field, including a topical update to two excellent books, The Ionotropic Glutamate Receptors and The Metabotropic Glutamate Receptors. An exciting primer on glutamate receptors and their central role in neurotransmission, The Glutamate Receptors covers the extraordinary research and significant developments in the decade since the previous books were published. It also offers a snapshot of where prominent scientists expect to see research heading in the future. Both insightful and comprehensive, this book provides an invaluable reference for students and scientists on nearly every aspect of glutamate receptor structure and function.

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Produktdetails

• Verlag: Humana Press
• Seitenzahl: 576
• Erscheinungstermin: 23. Februar 2008
• Englisch
• ISBN-13: 9781597450553
• Artikelnr.: 37348093

Autorenporträt

Glutamate receptors are critically important for normal brain function. The last decade has seen remarkable advances in our understanding of the physiological function and molecular structure of these proteins. This book provides a detailed review of the field, including a topical update to two excellent books, The Ionotropic Glutamate Receptors and The Metabotropic Glutamate Receptors. An exciting primer on glutamate receptors and their central role in neurotransmission, The Glutamate Receptors covers the extraordinary research and significant developments in the decade since the previous books were published. It also offers a snapshot of where prominent scientists expect to see research heading in the future. Both insightful and comprehensive, this book provides an invaluable reference for students and scientists on nearly every aspect of glutamate receptor structure and function.

Inhaltsangabe

AMPA Receptors.- NMDA Receptors.- Kainate Receptors.- Delta Receptors.- Ionotropic Glutamate Receptors in Synaptic Plasticity.- Structural Correlates of Ionotropic Glutamate Receptor Function.- Positive Modulators of AMPA-Type Glutamate Receptors.- Clinically Tolerated Strategies for NMDA Receptor Antagonism.- The Structures of Metabotropic Glutamate Receptors.- Group I Metabotropic Glutamate Receptors (mGlu1 and mGlu5).- Group II Metabotropic Glutamate Receptors (mGlu2 and mGlu3).- Group III Metabotropic Glutamate Receptors (mGlu4, mGlu6, mGlu7, and mGlu8).- Metabotropic Glutamate Receptor-Dependent Synaptic Plasticity.- Metabotropic Glutamate Receptor Ligands as Novel Therapeutic Agents.

Rezensionen

From the reviews:

"This is intended as a comprehensive primer for scientists and students studying the glutamate receptors. ... The book provides a good working knowledge of these receptors for all potential neuroscientist readers. ... it likely will best serve as a review for active researchers in the field of neuroscience. ... this book provides a timely update reflecting significant progress in the research in this field. ... an excellent resource for reviews on the neurobiology of individual receptor systems." (Kenneth E. McCarson, Doody's Review Service, June, 2007)