Roger O. McClellan

Tobacco-Specific N-Nitrosamines Recent Advances (eBook, PDF)

• Format: PDF

Produktbeschreibung

This remarkable book provides updates on various aspects of tobacco - its chemical and biological nature, and its physiological effects.

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Produktdetails

• Verlag: Taylor & Francis eBooks
• Seitenzahl: 85
• Erscheinungstermin: 6. Oktober 2017
• Englisch
• ISBN-13: 9781351408080
• Artikelnr.: 49985626

Autorenporträt

McClellan\, Roger O.

Inhaltsangabe

1. Introduction 2. Formation and Analysis of Tobacco-Specific N-Nitrosamines 3. Synthesis of Tobacco-Specific N-Nitrosamines and Their Metabolites and Results of Related Bioassays 4. Endogenous Formation of Nitrosamines and Oxidative DNA-Damaging Agents in Tobacco Users 5. Recent Studies on Mechanisms of Bioactivation and Detoxification of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone (NNK), A Tobacco-Specific Lung Carcinogen 6. Epidemiology of Cancer by Tobacco Products and the Significance of TSNA 7. The Biological Significance of Tobacco-Specific N-Nitrosamines: Smoking and Adenocarcinoma of the Lung 8. Comparative Carcinogenicity, Metabolism, Mutagenicity, and DNA Binding of 7H-Dibenzo[c,g]carhazole and Dibenz[a,j]acridine 9. Concluding Remarks

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1. Introduction 2. Formation and Analysis of Tobacco
Specific N
Nitrosamines 3. Synthesis of Tobacco
Specific N
Nitrosamines and Their Metabolites and Results of Related Bioassays 4. Endogenous Formation of Nitrosamines and Oxidative DNA
Damaging Agents in Tobacco Users 5. Recent Studies on Mechanisms of Bioactivation and Detoxification of 4
(Methylnitrosamino)
1
(3
Pyridyl)
1
Butanone (NNK), A Tobacco
Specific Lung Carcinogen 6. Epidemiology of Cancer by Tobacco Products and the Significance of TSNA 7. The Biological Significance of Tobacco
Specific N
Nitrosamines: Smoking and Adenocarcinoma of the Lung 8. Comparative Carcinogenicity, Metabolism, Mutagenicity, and DNA Binding of 7H
Dibenzo[c,g]carhazole and Dibenz[a,j]acridine 9. Concluding Remarks