Transcriptomics in Atherosclerosis (eBook, ePUB)

Deciphering Molecular Signatures and Advancing Therapeutic Strategies
Redaktion: Devaux, Yvan; Sopic, Miron

• Format: ePub

Produktbeschreibung

Transcriptomics in Atherosclerosis: Deciphering Molecular Signatures and Advancing Therapeutic Strategies integrates transcriptomic research and RNA-based therapeutics to understand and treat atherosclerosis. Emphasizing the power of genetic insights to revolutionize cardiovascular medicine, this book fills an essential gap by offering up-to-date insights into molecular mechanisms, diagnostic innovations, and therapeutic strategies, fostering a new era of personalized cardiovascular care. It addresses cutting-edge RNA sequencing methods, clinical translation, multi-omics integration, phenotyping, and treatment stratification, providing a holistic view of vascular pathology. Other important points include a focus on RNA-based biomarkers and therapeutics for early detection, monitoring, and targeted interventions in atherosclerosis.Readers will find advanced transcriptomic technologies, including single-cell and spatial transcriptomics, which unveil the complexities of atherosclerotic disease. The book promises to be a valuable resource for medical professionals seeking to deepen their knowledge in this burgeoning field. - Unravels the molecular intricacies of atherosclerosis using the latest transcriptomic technologies, offering new perspectives on disease mechanisms and potential therapeutic targets - Highlights the transformative potential of RNA molecules in advancing diagnostics and developing novel RNA-based treatments for personalized medicine in cardiovascular care - Provides actionable insights into translating transcriptomic findings into clinical applications, enhancing patient stratification and treatment strategies

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 300
• Erscheinungstermin: 1. September 2025
• Englisch
• ISBN-13: 9780443330650
• Artikelnr.: 75741108

Inhaltsangabe

Section I - Introduction
1. Atherosclerotic CVD - epidemiology and current challenges in management
2. Atherosclerotic Plaque Phenotypes: Unraveling Complexity and
Heterogeneity
Section II - The role of RNAs in atherosclerosis progression and
development
3. Biogenesis and mechanisms of action of ncRNAs
4. The role of ncRNA in plaque development and progression
5. Signaling Pathways Regulating Gene Expression in Atherosclerosis
6. Epitranscriptomics and Atherosclerosis:
Section III - Transcriptomic Profiling of Atherosclerotic Lesions
7. Essentials of Transcriptomic Methods: Navigating Through RNA Sequencing
and Beyond
8. Bridging the Gap in Transcriptomics: From Animal to Human Studies in
Atherosclerosis
9. Translating Transcriptomics into Clinical Practice: Utilizing Gene
Expression Patterns for Advanced Patient Phenotyping and Stratification in
Atherosclerosis Optimizing Study Design for In-depth Transcriptomic
Analysis of Atherosclerotic Plaques
10. Unveiling Sex-Specific Transcriptomic Mechanisms in Atherosclerosis
Section IV - Integrating Multi-Omics Approaches in Atherosclerosis Research
11. Combining Transcriptomics with Genomics, Proteomics, and Metabolomics
12. Insights into Gene Regulatory Networks in Vascular Pathology
13. Systems Biology and Network Analysis
14. Use of artificial intelligence and machine learning for multi-omics
Section V - RNA-Based Theranostics: Revolutionizing Treatment and Diagnosis
in Atherosclerotic Cardiovascular Disease
15. RNA Therapeutics in Atherosclerosis:
16. RNA Therapeutic Delivery Systems - advances and challenges
17. Exploring Circulating RNAs: Emerging Biomarkers for Atherosclerosis
Detection and Monitoring
Section VI - Conclusion
18. Future Directions and Emerging Technologies in Transcriptomic Research
and Atherosclerosis