Transdermal Fentanyl (eBook, PDF)

A New Approach to Prolonged Pain Control
Redaktion: Lehmann, Klaus A.; Zech, Detlev

• Format: PDF

Produktbeschreibung

That pain is a serious clinical problem, which requires considerable effortsby physicians and the nursing staff, has been stressed in numerous publications. Transdermal application is well known for a variety of drugs, including cardiovascular drugs, antiemetics and hormones. Some years ago, first experience was also made with transdermally administered opiates from which the transdermal therapeutic system (TTS) fentanyl has now been approved by the American Food and Drug Administration. The book presents the results of the first international workshop "Transdermal Fentanyl", held September 27 -28, 1990 in Cologne, FRG. This workshop was intended to facilitate a critical evaluation of theoretical and clinical studies with the new, non-invasive fentanyl application and to provide an opportunity for an exchange of ideas about its value for pain management, anaesthesiology and future investigations in this field. Topics covered by the book are physiology of transdermal permeation, experience with other transdermal systems, the present state of acute and chronic pain management and experimental and clinical studies with transdermal fentanyl, with special concern to analgesic efficacy and side effects. Readers will easily find out that the experts appreciated transdermal analgesia but also warned against an uncritical optimism. TTS fentanyl can be a valuable tool in the clinicians' armentarium against pain. It should be kept in mind, however, that it represents a new administration mode, not a new drug, and that the sustained, non-invasive application requires well reflected diagnosis and good general standards of pain management.

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Produktdetails

• Verlag: Springer Berlin Heidelberg
• Seitenzahl: 203
• Erscheinungstermin: 6. Dezember 2012
• Englisch
• ISBN-13: 9783642768729
• Artikelnr.: 53334008

Inhaltsangabe

I Transdermal Therapeutic Systems - An Introduction.- Transdermal Permeation: Physiological and Physicochemical Aspects.- Transdermal Therapeutic Systems in Clinical Use: Development and Applications.- II Current Aspects of Pain Management.- Postoperative Pain.- Cancer Pain.- Pain Management and Quality of Life in Cancer Patients.- Opioid Analgesia for Chronic, Nonmalignant Pain.- III Noninvasive Fentanyl Application.- Pharmacokinetics of Fentanyl.- Premedication and Pain Management with Oral Transmucosal Fentanyl.- Transdermal Fentanyl: an Overview of Pharmacokinetics, Efficacy and Safety.- IV Postoperative Pain Management with TTS Fentanyl.- Pharmacokinetics and Pharmacodynamics.- Clinical Experience.- Respiratory Safety.- TTS Fentanyl in Combination with Patient-Controlled Analgesia.- V Cancer Pain Management with TTS Fentanyl.- Clinical Experience.- VI Other Transdermal Therapeutic Systems for Anesthesia and Pain Management.- Local Anesthetics: Eutectic Mixture of Local Anesthetics.- Scopolamine.