Treatments from Toxins (eBook, PDF)

The Therapeutic Potential of Clostridial Neurotoxins
Redaktion: Foster, Keith Alan; Shone, Clifford C.; Hambleton, Peter

• Format: PDF

Produktbeschreibung

As little as two decades ago, deliberately injecting botulinum toxin into patients would have seemed foolhardy at best and criminal at worst. The increased clinical use of botulinum toxins has expanded the body of knowledge available on the structure and function of these proteins. This knowledge can be applied to topics as varied as therapies base

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Produktdetails

• Verlag: Taylor & Francis eBooks
• Seitenzahl: 312
• Erscheinungstermin: 2. November 2006
• Englisch
• ISBN-13: 9781420004151
• Artikelnr.: 53306676

Autorenporträt

Keith Alan Foster, Peter Hambleton, Clifford C. Shone

Inhaltsangabe

Introduction and Historical Perspective. Three-Dimensional Protein
Structures of Light Chains of Botulinum Neurotoxin Serotypes A, B, and E
and Tetanus Neurotoxin. Mechanisms of Actions of Neurotoxins. Vaccines to
Protect against Neurotoxins. Inhibitors of Clostridial Neurotoxin
Proteinase Activities. Introduction to Clinical Use of Botulinum
Neurotoxins. Expanding Clinical Uses of Botulinum Neurotoxins. Development
of Therapeutics Based upon Clostridial Endopeptidase Activity. Use of
Neurotoxins as Drug Delivery Systems. Conclusions and Future Perspectives:
Botulinum Neurotoxins as Paradigms for Development of Microbial
Effector-Derived Drugs. Index.