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This monograph, for the first time, presents a comprehensive overview of different mechanisms of immune dysfunction in cancer as well as therapeutic approaches to their correction. It discusses a number of new mechanisms that have never been discussed in a monograph before: T-cell inhibitory molecules, regulatory tolerogenic DCs, and signaling pathways in antigen-presenting cells involved in T-cell tolerance. The book addresses a pressing need to discuss the already described and newly emerging mechanisms to see how they can be put together in a more or less cohesive structure, and how they can help to improve immune response to tumors.…mehr

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Produktbeschreibung
This monograph, for the first time, presents a comprehensive overview of different mechanisms of immune dysfunction in cancer as well as therapeutic approaches to their correction. It discusses a number of new mechanisms that have never been discussed in a monograph before: T-cell inhibitory molecules, regulatory tolerogenic DCs, and signaling pathways in antigen-presenting cells involved in T-cell tolerance. The book addresses a pressing need to discuss the already described and newly emerging mechanisms to see how they can be put together in a more or less cohesive structure, and how they can help to improve immune response to tumors.


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